Latest PLoS Medicine Stories
A new extension to the PRISMA guideline on reporting systemic reviews and meta-analyses (types of studies that analyze information from many studies) will help authors to give a more robust summary (abstract) of their study and is detailed by an international group of researchers in this week's PLOS Medicine.
A vaccine to prevent shingles may reduce by half the occurrence of this painful skin and nerve infection in older people (aged over 65 years) and may also reduce the rate of a painful complication of shingles, post-herpetic neuralgia, but has a very low uptake (only 4%) in older adults in the United States.
In South Africa, people with HIV who start treatment with anti-AIDS drugs (antiretroviral therapy) have life expectancies around 80% of that of the general population provided that they start treatment before their CD4 count drops below 200 (cells per microliter).
A new international study has confirmed that self-testing for HIV is effective and could be the answer to controlling the global epidemic.
In Africa, issues of vaccine supply, financing, and sustainability require urgent attention if the Millennium Development Goals are to be achieved.
For medicines intended for chronic use, the number of patients studied before regulatory approval is insufficient to properly evaluate safety and long-term efficacy, requiring the need for new legislation.
In low-income countries a substantial challenge in planning and delivering healthcare is the accurate assessment of disease burden.
A study published this week in PLOS Medicine finds that while antipsychotic medications are associated with small-to-moderate improvements in depressive symptoms in adults, there is little evidence for improvement on measures of quality of life and these medications are linked to adverse events such as weight gain and sedation.
Early diagnosis and treatment with antimalarial drugs (ACTs—artemisinin based combination treatments) has been linked to a reduction in malaria in the migrant population living on the Thai-Myanmar border, despite evidence of increasing resistance to ACTs in this location.
A simple new method better assesses the risks posed by emerging zoonotic viruses (those transmissible from animals to humans).
PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...
PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...