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Latest PLoS ONE Stories

2013-12-24 13:28:00

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells. In this early proof-of-concept study, the scientists have shown that they can target tumor blood vessels in mice without affecting healthy tissues. "Most current gene therapies in humans involve...

2013-12-19 12:08:10

Three stakeholder groups agree that regulators are not adequately prepared to manage the risks posed by nanotechnology, according to a paper published in the peer-reviewed journal PLOS One. In a survey of nano-scientists and engineers, nano-environmental health and safety scientists, and regulators, researchers at the UCSB Center for Nanotechnology in Society (CNS) and at the University of British Columbia found that those who perceive the risks posed by nanotechnology as "novel" are more...

2013-12-19 11:42:36

Life expectancy of treated HIV-positive individuals approaches that of general population A 20-year-old HIV-positive adult on antiretroviral therapy (ART) in the U.S. or Canada may be expected to live into their early 70's, a life expectancy approaching that of the general population, according to results published December 18, 2013, in the open access journal PLOS ONE by Hasina Samji and colleagues from the British Columbia Centre for Excellence in HIV/AIDS (BC-CfE) and the North American...

2013-12-19 10:38:09

Biological markers confirm behavioral data; underscore drug's effectiveness In 2012 the HIV antiretroviral drug Truvada became the first and only medication approved by the FDA for HIV prevention. Led by Gladstone Institutes' Investigator Robert Grant, MD, MPH, this research was hailed as an important step towards reducing the worldwide HIV/AIDS epidemic. Now, a new study provides further proof that regular Truvada use can reduce one's risk for contracting HIV—without increasing sexual...

2013-12-18 15:15:20

Wildlife conservation projects in countries where management costs are low are less likely to succeed and could also have a negative impact on people, according to new research by the University of Kent and the University of California Santa Cruz (UCSC). Published in PLOS ONE and titled “Cheap and Nasty? The Potential Perils of Using Management Costs to Identify Global Conservation Priorities”, the research is the first to investigate links between conservation management costs and a...

2013-12-12 12:14:07

Pretreatment with near-infrared laser also could improve response to additional intradermal vaccines Pretreating the site of intradermal vaccination – vaccine delivered into the skin rather than to muscles beneath the skin – with a particular wavelength of laser light may substantially improve vaccine effectiveness without the adverse effects of chemical additives currently used to boost vaccine efficacy. In the open-access journal PLOS ONE, investigators from Vaccine and Immunotherapy...

2013-12-12 10:51:45

Poverty may have direct implications for important, early steps in the development of the brain, saddling children of low-income families with slower rates of growth in two key brain structures, according to researchers from the University of Wisconsin–Madison. By age 4, children in families living with incomes under 200 percent of the federal poverty line have less gray matter — brain tissue critical for processing of information and execution of actions — than kids growing up in...

2013-12-12 10:49:59

Genetic signature identifies patients with more aggressive triple-negative cancers A new test has the potential to help physicians identify patients with the most lethal forms of triple-negative breast cancer, a disease which requires aggressive and innovative treatment. The test, described in the Dec. 11 issue of PLOS ONE, was able to distinguish between patients with a good or poor prognosis, even within groups of patients already stratified by existing tests such as MammaPrint and...

2013-12-12 10:27:54

The degree to which students' exam scores differ owes more to their genes than to their teachers, schools or family environments, according to new research from King's College London published today in PLOS ONE. The study, which took place in the UK, looked at students' scores for their GCSE's (General Certificate of Secondary Education), a UK-wide examination at the end of compulsory education at 16 years old. The authors explain that the findings do not imply that educational...


Latest PLoS ONE Reference Libraries

PLoS Medicine
2012-05-17 15:12:48

PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...

PLoS Biology
2012-05-02 19:40:12

PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...

PLoS ONE
2012-04-30 14:56:25

PLoS ONE is an open-access peer-reviewed scientific journal published by the Public Library of Science (PLoS). It was established in 2006 as a beta version. In August 2008 it moved from a weekly publication schedule to a daily one, publishing articles as soon as they became ready. In October 2008, it came out of “beta.” In September 2009, PLoS ONE made full online usage of every published article publicly available. The founding managing editor was Chris Surridge. He was succeeded by...

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Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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