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Latest PLoS Pathogens Stories

2012-03-09 10:54:46

Study uses advanced gene-sequencing technologies to track viral evolution Mutations in HIV that develop during the first few weeks of infection may play a critical role in undermining a successful early immune response, a finding that reveals the importance of vaccines targeting regions of the virus that are less likely to mutate. A new study in the journal PLoS Pathogens, led by researchers at the Ragon Institute of Massachusetts General Hospital, MIT and Harvard and the Broad Institute...

2012-02-27 11:28:39

How subverting the immune system shapes the arms race between bacteria and hosts Why is it that Mycobacterium tuberculosis can cause tuberculosis with as little as 10 cells, whereas Vibrio cholerae requires the host to ingest up to tens of millions of cells to cause cholera? This is the question that two research teams, from the Pasteur Institute, in France, and the Instituto Gulbenkian de Ciencia and the University of Lisbon, in Portugal, answer in the latest issue of the journal PLoS...

2012-02-10 11:37:39

Scientists from Queen Mary, University of London have discovered the workings behind some of the bacteria that kill hundreds of thousands every year, possibly paving the way for new antibiotics that could treat infections more effectively. With antibiotic resistance on the rise in strains of pathogenic bacteria, innovative strategies are needed to discover ways of treating bacterial infections in both humans and in agriculture. Writing in the journal PLoS Pathogens, the team from Queen...

2012-02-10 10:27:26

A neuropeptide called Substance P is the cause of seizures in patients with brains infected by the pork tapeworm (Taenia solium), said Baylor College of Medicine researchers in a report that appears online in the open access journal PLoS Pathogens. "Neurocysticercosis or the tapeworm parasitic infection in the brain, is the major cause of acquired seizures," said Dr. Prema Robinson, assistant professor of medicine — infectious diseases, and corresponding author of the report. "It is...

2011-12-23 10:17:41

A research team led by Glenn Rall at the Fox Chase Cancer Center in Philadelphia, PA developed a novel mouse model to show that a fatal central nervous system (CNS) disease can be caused by a pathogen that does not replicate in the CNS. The results of this new study are published December 22nd in the Open Access journal PLoS Pathogens. The authors found that the immune response induced in response to a peripheral viral infection can be "mis-recruited" to the brain, where these activated...

2011-12-23 10:16:23

Researchers at the Johns Hopkins Malaria Research Institute have demonstrated that the Anopheles mosquito's innate immune system could be genetically engineered to block the transmission of malaria-causing parasites to humans. In addition, they showed that the genetic modification had limited impact on the mosquito's fitness under laboratory conditions. The researchers' findings are published December 22nd in the Open Access journal PLoS Pathogens. In this study, Dimopoulos and his team...

2011-12-10 01:49:36

• The study focuses on the protein Ler, which is present in the pathogenic strains of Escherichia coli that caused an outbreak of food poisoning in Germany last May. • Ler binds multiple DNA sequences, thereby activating numerous genes responsible for bacterial virulence. • The findings of the study have been published in PloS Pathogens. A team headed by scientists from the Institute for Research in Biomedicine (IRB Barcelona) reports how the protein Ler, which is...

2011-12-09 14:59:21

Scientists have found the 'key' that HIV uses to enter our cells' nuclei, allowing it to disable the immune system and cause AIDS. The finding, published today in the open access journal PLoS Pathogens, provides a potential new target for anti-AIDS drugs that could be more effective against drug-resistant strains of the virus. HIV is transmitted through bodily fluids, primarily infected blood or semen. Once inside the bloodstream, the virus infects key components of the immune system...

2011-11-17 10:24:19

Bacteria responsible for middle ear infections, pink eye and sinusitis protect themselves from further immune attack by transporting molecules meant to destroy them away from their inner membrane target, according to a study from Nationwide Children's Hospital. The study, published in the November issue of PLoS Pathogens, is the first to describe a transporter system that bacteria use to ensure their survival. When the body senses an infection, one of the first lines of defense is to send...

2011-11-11 18:25:13

Infectious diseases specialists from Austin Health are working closely with Microbiologists from the University of Melbourne to understand how Staph is becoming resistant to all antibiotic therapies. The treatment of serious infections caused by Staphylococcus aureus (Golden Staph) is complicated by the development of antibiotic resistance. Seriously ill patients, vulnerable to infections can be at additional risk if antimicrobial agents become less effective in fighting infections....


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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