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Latest Pluripotency Stories

2011-01-13 14:36:35

Scientists have developed Australia's first adult induced pluripotent stem cell lines using skin biopsies from patients with the rare genetic disease Friedreich Ataxia (FA). The study was conducted by the University of Melbourne and Monash Institute of Medical Research and is published in the current online edition of the international journal Stem Cell Reviews and Reports. It is the first time adult pluripotent stem cells, known as iPS cells have been developed for a specific disease in...

2011-01-06 16:46:57

A multinational team of researchers led by stem cell scientists at the University of California, San Diego School of Medicine and Scripps Research Institute has documented specific genetic abnormalities that occur in human embryonic (hESC) and induced pluripotent stem cell (iPSC) lines. Their study, "Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture" will be published in the January 7 issue of the...

2011-01-06 06:00:00

MADISON, Wis., Jan. 6, 2011 /PRNewswire/ -- Cellular Dynamics International, Inc. (CDI), the world's largest producer of human induced pluripotent stem (iPS) cell lines and tissue cells for drug discovery and safety, today announced that the company is scheduled to present at the 29th Annual JPMorgan Healthcare Conference at 7:30 a.m. PST, Thursday, January 13, at the Westin St. Francis Hotel in San Francisco. Robert Palay, chief executive officer of CDI, and Emile Nuwaysir, chief operating...

2011-01-05 09:00:00

LEXINGTON, Ky., Jan. 5, 2011 /PRNewswire/ -- Transposagen Biopharmaceuticals, Inc. (Transposagen), a leader in genetic modification technology, announced today that it has entered into a non-exclusive license agreement with Cellular Dynamics International (CDI), the world's largest producer of human induced pluripotent stem (iPS) cell lines and tissue cells for drug discovery and safety. The license agreement allows CDI to use Transposagen's piggyBac technology in the creation of its...

2011-01-04 09:00:00

YOKOHAMA, Japan, January 4, 2011 /PRNewswire/ -- ReproCELL, Inc. (CEO: Chikafumi Yokoyama PhD) announces today that the company will enter a collaborative R&D agreement with the National Institute of Biomedical Innovation (NIBIO; Director General: Koichi Yamanishi; Osaka, Japan), which could offer new hepatocyte derived from human iPS (induced pluripotent stem) cells used for an effective in-vitro drug screening for hepatic toxicity and liver metabolism. ReproCELL is a...

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2010-12-31 06:30:00

Two American companies broke new ground this year by gaining regulatory approval to begin the first experiments using embryonic stem cells on people suffering from spinal cord injuries and blindness. The use of the cells, which have been hotly debated for years, can transform into nearly any cell in the human body, which could lead to finding ways to eliminate such ailments as Parkinson's disease, diabetes, heart disease, paralysis, and may even help fight aging. As scientists find ways to...

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2010-12-16 10:09:14

University of Illinois researchers have found a key to keeping stem cells in their neutral state: It takes a soft touch. In a paper published in the journal PLoS One, the researchers demonstrated that culturing mouse embryonic stem cells (mESCs) on a soft gel rather than on a hard plate or dish keeps them in their pluripotent state, a ground state with the ability to become any type of tissue. The soft substrate maintains homogeneous pluripotent colonies over long periods of time "“...

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2010-12-13 10:20:00

In two separate studies, researchers at Georgetown University and the Cincinnati Children's Hospital Medical Center have been able to create pancreatic cells and intestinal tissue from human stem cells, illustrating a pair of new uses for the potent, self-replicating building blocks. In the first study, researchers at the Georgetown University Medical Center (GUMC) report that they were able to create insulin-secreting pancreatic islet cells from testicular tissue. The achievement, which was...

2010-12-12 13:00:00

CINCINNATI, Dec. 12, 2010 /PRNewswire-USNewswire/ -- For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells. In a study posted online Dec. 12 by Nature, scientists from Cincinnati Children's Hospital Medical Center say their findings will open the door to unprecedented studies of human intestinal development, function and disease. The process is also a significant step toward generating intestinal tissue for...

2010-12-09 20:12:38

Remarkable progress in understanding how stem cell biology works has been reported by a team of leading scientists, directed by experts at UC Santa Barbara. Their research has been published in the journal Cell Stem Cell. Stem cell biology is making waves around the world with great hope for the eventual repair of parts of the body. While many scientists see these breakthroughs as viable, there are hurdles that must be overcome, including the worrisome potential for introducing cancer when...