Quantcast
Last updated on April 16, 2014 at 13:57 EDT

Latest Pluripotency Stories

2011-10-14 09:05:22

Ordinarily, embryonic stem cells exist only a day or two as they begin the formation of the embryo itself. Then they are gone. In the laboratory dish, however, they act more like perpetual stem cells — renewing themselves and exhibiting the ability to form cells of almost any type, a status called totipotency. Dr. Thomas Zwaka, associate professor in the Stem Cell and Regenerative Medicine Center at Baylor College of Medicine, and his colleagues here and abroad showed that...

2011-10-14 06:40:38

(Ivanhoe Newswire) — Can researchers predict the future of stem cells by knowing how they begin?  Dr.Thomas Zwaka, associate professor in the Stem Cell and Regenerative Medicine Center at Baylor College of Medicine, and his colleagues examined the cells of mice and showed that laboratory-grown cells express a protein called Blimp1, which represses differentiation to specific or regular tissue cells during germ cell development. Embryonic stem cells exist only a day or two as...

2011-10-06 13:15:15

Mass. General/Harvard study shows Sox2 expression is a widespread marker of adult stem cells Investigators at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI) have found that Sox2 — one of the transcription factors used in the conversion of adult stem cells into induced pluripotent stem cells (iPSCs) — is expressed in many adult tissues where it had not been previously observed. They also confirmed that...

Cloning Used To Create Human Stem Cells
2011-10-06 05:31:18

Scientists have for the first time used a form of cloning to create personalized embryonic stem cells, an important advancement that could impact the study and treatment of diseases such as diabetes, Parkinson´s and Alzheimer´s. The researchers derived embryonic stem cells from individual patients by adding the nuclei of adult skin cells from patients with type-1 diabetes to unfertilized donor oocytes. Stem cells are primitive cells that differentiate into the various tissues...

Image 1 - Muscles Reprogrammed To Combat Degeneration
2011-09-23 03:21:35

  Researchers at the University of California, Berkeley, have turned back the clock on mature muscle tissue, coaxing it back to an earlier stem cell stage to form new muscle. Moreover, they showed in mice that the newly reprogrammed muscle stem cells could be used to help repair damaged tissue. The achievement, described in the Sept. 23 issue of the journal Chemistry & Biology, "opens the door to the development of new treatments to combat the degeneration of muscle associated...

2011-09-20 06:00:00

MADISON, Wis., Sept. 20, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the commercial launch of human iCell® Endothelial Cells for use in vascular-targeted drug discovery, tissue regeneration and other life science research. Endothelial cells make up the lining of blood vessels and thus are an important factor of vascular research across a multitude of disease states. Endothelial dysfunction is a common promoter of cardiovascular disease,...

2011-09-15 20:16:08

Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single event in a process called alternative splicing. Alternative splicing allows one gene to generate many different genetic messages and protein products. The researchers found that in genetic messages of a gene called FOXP1, the switch was active in embryonic stem cells...

Critical Similarity Found Between Two Types Of Do-it-all Stem Cells
2011-09-12 07:37:12

  Ever since human induced pluripotent stem cells were first derived in 2007, scientists have wondered whether they were functionally equivalent to embryonic stem cells, which are sourced in early-stage embryos. Both cell types have the ability to differentiate into any cell in the body, but their origins — in embryonic and adult tissue — suggest that they are not identical. Although both cell types have great potential in basic biological research and in cell- and...

2011-09-06 08:17:00

NEW YORK, Sept. 6, 2011 /PRNewswire/ -- Americord Registry, a leader in the advancement of cord blood and placenta stem cell preservation, has announced the expansion of its Medical Advisory Board with the appointment of Dr. Eric Adler, who previously served as Interim Medical Director for the company. Dr. Adler will assist with operations related to induced pluripotent stem cell (or iPS stem cells) preservation, which have the benefits of embryonic stem cells but are derived from a...

2011-08-29 12:11:44

Global view of 'lincRNAs' reveals critical role in regulation of embryonic stem cells Scientists at the Broad Institute of MIT and Harvard have discovered that a mysterious class of large RNAs plays a central role in embryonic development, contrary to the dogma that proteins alone are the master regulators of this process. The research, published online August 28 in the journal Nature, reveals that these RNAs orchestrate the fate of embryonic stem (ES) cells by keeping them in their...