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Latest Pluripotency Stories

2011-08-17 13:20:43

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue. The researchers, from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, found that the progeny of the human embryonic stem cells and induced...

2011-08-15 12:19:46

Like fine chefs, scientists are seemingly approaching a day when they will be able to make nearly any type of tissue from human embryonic stem cells. You need nerves or pancreas, bone or skin? With the right combination of growth factors, skill and patience, a laboratory tissue culture dish promises to yield therapeutic wonders. But within these batches of newly generated cells lurks a big potential problem: Any remaining embryonic stem cells - those that haven't differentiated into the...

2011-08-11 07:30:00

MADISON, Wis., Aug. 11, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) announced today the recent launch of its Innovative Research Grant Program. This grant program will advance researchers' understanding of induced pluripotent stem cells (iPSCs), the terminal cell types derived from them, and the role and applications of this new in vitro cellular model in basic research, drug discovery and development. "The off-the-shelf availability of high quality human cell models for...

2011-08-10 06:44:15

(Ivanhoe Newswire) "“ New scientific findings are crucial for infertility research and treatment and for a more comprehensive understanding of germ cell biology in general. Researchers have now found a way to turn mouse embryonic stem cells into sperm. Investigators coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and discovered that these cells were able to produce healthy sperm. The researchers say that such in vitro reconstitution of germ...

2011-08-04 14:03:25

Researchers have found a way to turn mouse embryonic stem cells into sperm. This finding, reported in the journal Cell in a special online release on August 4th, opens up new avenues for infertility research and treatment. A Kyoto University team has coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one...

2011-07-19 13:20:54

Scientists at the Keck School of Medicine of USC grow brain cells from skin Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells. Scientists at the Keck School of Medicine of the University of Southern California (USC) have proven that those genes also can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy. "The...

2011-07-13 23:25:15

Adult-derived stem cells could pave the way for new treatment of diabetes, says TAU researcher Stem cells from early embryos can be coaxed into becoming a diverse array of specialized cells to revive and repair different areas of the body. Therapies based on these stem cells have long been contemplated for the treatment of diabetes, but have been held back by medical and ethical drawbacks. Now researchers at Tel Aviv University are capitalizing on the "memories" of stem cells generated from...

2011-07-07 20:27:20

Pluripotent cells are not all equal Human stem cells have the ability to become any cell type in the human body, but when it comes to their destination they know where they want to go. This finding by McMaster University researchers sheds new light on how these regenerative cells turn into more specialized cell types, such as neural or blood cells. Until now, the thought has been that stem cells keep all their options open and have no preference when it comes to becoming more specialized. In...

2011-07-05 06:00:00

MADISON, Wis., July 5, 2011 /PRNewswire/ -- The Medical College of Wisconsin (MCW) and Cellular Dynamics International (CDI) today announced receipt of a research grant award from the National Heart, Lung, and Blood Institute (NHLBI) to investigate the mechanisms underlying Left Ventricular Hypertrophy. Commonly known as an increase of the size and weight of the heart, Left Ventricular Hypertrophy is a common and major risk factor for heart disease and heart failure due to high blood...

2011-06-27 06:00:00

MADISON, Wis., June 27, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the online publication of an article in the journal Blood demonstrating for the first time a methodology for researchers to access the biology stored in repositories of banked blood samples through the creation of induced pluripotent stem cells (iPSCs). According to the article, entitled "Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells," the derived...