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Latest Pluripotency Stories

2011-03-22 07:00:00

MADISON, Wis., March 22, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) announced today that their two-year collaboration with Roche (SIX: RO, ROG; OTCQX: RHHBY) to substantiate CDI's iCell® Cardiomyocytes as a predictive tool for assessing the potential cardiotoxic effects of developing drug candidates was completed early and is now transitioning into a standard supply agreement. Moving forward, iCell Cardiomyocytes, induced pluripotent stem cell...

2011-03-08 11:00:00

PARIS, March 8, 2011 /PRNewswire/ -- Cellectis (Alternext: ALCLS), the genome engineering specialist, and Etablissement Francais du Sang (EFS), the only civilian blood transfusion service in France, announce that StemRed, an ambitious collaborative program to produce red blood cells from induced pluripotent stem cells (iPS cells) has started on March 1. This program, which also involves Pierre and Marie Curie University (UPMC), Bertin Technologies and CECS (Centre d'Etude des Cellules...

2011-03-07 15:18:09

In the past few months, a slew of papers have indicated that the therapeutic potential of a promising type of stem cell, called induced pluripotent stem (iPS) cells, might be limited by reprogramming errors and genomic instability. iPS cells are engineered by reprogramming fully differentiated adult cells, often skin cells, back to a primitive, embryonic-like state. Given these problems, a team of researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham), Chung-Ang...

2011-03-07 14:24:45

The diagnostic test enables accurate, rapid assessment of the quality of stem cell lines "Pluripotent" stem cells"”which have the potential to mature into almost any cell in the body"”are being widely studied for their role in treating a vast array of human diseases and for generating cells and tissues for transplantation. Now, a team of Scripps Research Institute scientists has created a quality control diagnostic test that will make it much easier for researchers to determine...

2011-03-04 08:30:00

MADISON, Wis., March 4, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI), the world's largest producer of human tissue cells for drug discovery and safety testing, today announced the publication of research demonstrating an efficient and scalable method of creating DNA integration-free, or footprint-free, induced pluripotent stem cells (iPSCs) under a feeder-free condition using chemically defined media. This method, published on March 1 in PLoS ONE, will likely be valuable for...

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2011-02-28 08:07:04

Discovery opens avenue for research into new veterinary and human treatments for a range of degenerative conditions In a world first, pluripotent stem cells have been generated from horses by a team of researchers led by Dr. Andras Nagy at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and Dr. Lawrence Smith at the University of Montreal's Faculty of Veterinary Science. The findings will help enable new stem-cell based regenerative therapies in veterinary medicine, and...

2011-02-03 20:40:26

Ever since researchers devised a recipe for turning adult cells into cells that look and act like embryonic stem cells, there has been lingering doubt in the field about just how close to embryonic stem cells each of those cell lines really is at a molecular and functional level. Now, researchers reporting in the February 4th issue of the journal Cell, a Cell Press publication, have developed a systematic way to lay those doubts about quality to rest. They have devised a method to quickly and...

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2011-02-03 13:30:00

A new study to generate replacement tissue in the lab faced questions on Thursday over mature cells whose DNA is "reprogrammed" so that they grow with youthful vigor into new cells. Last year, cellular reprogramming emerged as the new frontier in the heavily promoted search to grow cells to replenish organs. Scientists announced in 2010 that they had been able to wipe out the DNA programming of mature cells, yielding versatile stem cells that would be the raw material for organ-specific...

2011-02-02 20:32:41

Reprogramming adult cells to recapture their youthful "can-do-it-all" attitude appears to leave an indelible mark, found researchers at the Salk Institute for Biological Studies. When the team, led by Joseph Ecker, PhD., a professor in the Genomic Analysis Laboratory, scoured the epigenomes of so-called induced pluripotent stem cells base by base, they found a consistent pattern of reprogramming errors. What's more, these incompletely or inadequately reprogrammed hotspots are maintained when...

2011-01-31 13:19:47

Breakthrough discovery offers hope for new therapies for range of diseases Scripps Research Institute scientists have converted adult skin cells directly into beating heart cells efficiently without having to first go through the laborious process of generating embryonic-like stem cells. The powerful general technology platform could lead to new treatments for a range of diseases and injuries involving cell loss or damage, such as heart disease, Parkinson's, and Alzheimer's disease. The work...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.