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Latest polycystic kidney disease Stories

2011-12-06 23:17:59

Research presented at ASCB annual meeting After a four-week course of the vasodilator hormone relaxin, kidney function and blood flow immediately improved in lab rats genetically altered to model polycystic kidney disease (PKD), a life-threatening genetic disorder, according to research presented on Dec. 6 at the American Society for Cell Biology Annual Meeting in Denver. In addition to widening the blood vessels, relaxin lowered the collagen scores of the PKD rats, indicating that the...

2011-10-25 09:55:05

The gene that's implicated in the disease is important for signaling in the kidneys Babies born with autosomal recessive polycystic kidney disease (ARPKD) often develop kidney failure because they have very large kidneys filled with tiny cysts. Even with excellent medical care, about 30% die shortly after birth. New research now provides clues into how gene defects may cause this condition, which occurs in 1 out of 20,000 newborns. The findings appear in an upcoming issue of the Journal of...

2011-10-25 09:46:04

Genetic testing could identify children at risk The most common kidney disease passed down through families, autosomal dominant polycystic kidney disease (ADPKD) affects one in 400 to 1,000 individuals and is characterized by cysts on the kidneys. The condition slowly gets worse and leads to kidney failure. Most ADPKD cases arise in adults, but some patients show severe symptoms of the disease in early childhood. New research indicates that these severely affected patients carry, in...

2011-06-20 12:47:23

A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics. The findings suggest manipulating activity of PKD1, the gene causing the most common form of polycystic kidney disease, may prove beneficial in reducing cysts in both liver and kidney. "We found that these conditions are not the result of an all or nothing phenomenon," said Stefan Somlo, the C.N.H. Long...

2011-06-13 15:44:08

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology (www.jcb.org). Aurora A is an oncogene best known as a regulator of mitotic progression. But the kinase has important functions during interphase as well, when it can promote cilia disassembly and can be activated by elevated calcium levels. Because both calcium signaling and cilia are defective in...

2011-05-22 00:02:20

LivFest is back! This Saturday, May 21, Village Green in Fairhaven will be jammin' all day for the LivFest 2011 fundraiser. Starting at 10:30 in the morning and going until 9:30 at night, there will be 14 live bands, arts & crafts, kids' activities and great food to eat, including upscale tacos and more from StrEAT Food. Proceeds will go to the Children's Organ Transplant Association in honor of Olivia Cook, now thriving with her new kidney. Bellingham, WA (PRWEB) May 20, 2011 StrEAT...

2011-05-16 15:56:41

Stem cell research courts both controversy and support in the community- depending on your viewpoint. Now, for the first time, scientists at Monash University's Immunology and Stem Cell Laboratories (MISCL) have shown that they can make human stem cells from healthy adult kidneys without working on human embryos, circumventing ethical concerns around this research. This achievement will allow group leader Associate Professor Sharon Ricardo and her team to model genetic kidney diseases in the...

2011-02-24 09:38:00

KANSAS CITY, Mo., Feb. 24, 2011 /PRNewswire-USNewswire/ -- The PKD Foundation is today announcing that Mr. Dan Larson will be retiring from his long-time position as the Foundation's President and CEO, and will be transitioning into a new role as the Foundation's Senior Advisor and CEO-Emeritus. Mr. Larson began his work at the PKD Foundation in 1993, and has served as its President and CEO since 1994. In that role, he has directed the transformation of the organization from a small,...


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