Latest Polymerase Stories

The novel Natural Sciences Bibliographic Web Portal aims to provide comprehensive bibliographic information on the basic and applied life, earth and health sciences and has published over 184,800 references and 133,600 tags. Scien.net has now newly included the category Polymerase which is an enzyme associated with polymers of nucleic acids such as the deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), and on Reductase, which is an enzyme that is known for catalyzing reduction and...

redOrbit Staff & Wire Reports - Your Universe Online Scientists at Penn State University have discovered how a vital step in the human DNA replication process – the loading of molecular structures known as sliding clamps onto DNA molecules – is performed. The researchers say their work, the results of which were published in Tuesday’s edition of the journal eLife, will help uncover some of the mystery surrounding this crucial part of the chemical replication process. This step...

IPSWICH, Mass., Aug. 8, 2012 /PRNewswire/ -- New England Biolabs (NEB) has released a novel DNA polymerase, Q5((TM)) High-Fidelity DNA Polymerase, that provides the highest fidelity amplification currently available, while also offering robust amplification across the broadest range of amplicons, including those that are GC- and AT-rich. (Photo: http://photos.prnewswire.com/prnh/20120808/NE54308 ) (Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) High fidelity...

St. Jude Children's Research Hospital study shows how compounds blocking an enzyme universal to all influenza viruses may allow development of new antiviral drugs that also avoid the problem of drug resistance Scientists at St. Jude Children's Research Hospital have reported details of how certain drugs can precisely target and inhibit an enzyme essential for the influenza virus' replication. Since all strains of the virus require the same functioning enzyme, researchers believe their...

The discovery made by Dr. François Robert's team confirms the universality of an essential cellular process Dr. François Robert, molecular biology researcher at the Institut de recherches cliniques de Montréal (IRCM), and his team confirmed that the phosphorylation of RNA polymerase II, a key enzyme in the process of gene expression, is uniform across all genes. This discovery, which contributes to numerous debates on the topic within the scientific community, will be published tomorrow...

New research published in BioMed Central's open access journal Cell & Bioscience is the first to show that left-handed Z-DNA, normally only found at sites where DNA is being copied, can also form on nucleosomes. The structure of DNA which provides the blueprint for life has famously been described as a double helix. To save space inside the nucleus, DNA is tightly wound around proteins to form nucleosomes which are then further wound and compacted into chromatin, which is further...

IPSWICH, Mass., Nov. 10, 2011 /PRNewswire/ -- New England Biolabs (NEB), in its continuing commitment to open access science, announces Polbase, a new, free and open database covering DNA polymerase biochemistry, genetics and structural biology. Inspired by REBASE (the Restriction Enzyme Database, also developed and maintained by NEB), Polbase summarizes the information that exists in the extensive body of polymerase literature, making it easy for researchers to interrogate and use. Polbase...

BOULDER, Colo., and IPSWICH, Mass., July 27, 2011 /PRNewswire/ -- SomaLogic, Inc. and New England Biolabs, Inc. (NEB) announce today that they have entered into an exclusive licensing agreement whereby SomaLogic will provide specific SOMAmers as critical and unique reagents in several current and future NEB nucleic acid amplification and polymerase chain reaction (PCR) products. (Logo: http://photos.prnewswire.com/prnh/20110727/NE42652LOGO ) (Logo:...

Scientists have deciphered the structure of an essential part of Mediator, a complex molecular machine that plays a vital role in regulating the transcription of DNA.The research adds an important link to discoveries that have enabled scientists to gain a deeper understanding of how cells translate genetic information into the proteins and processes of life. The findings, published in the July 3 advance online issue of the journal Nature, were reported by a research team led by Yuichiro...

A Berkeley Lab-led team deciphers the structure of FEN1, a key player in DNA replication and repairDNA replication is critical to the life of all organisms, insuring that each new cell, as well as each new offspring, gets an accurate copy of the genome. Among the legions of proteins that do the work so essential to a cell's survival, the DNA-slicing "flap endonuclease" FEN1 plays a key role.The structure of human FEN1 has now been solved by an international team of scientists led by...