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Latest Portal Hypertension Stories

2013-04-25 16:33:26

New data from clinical studies presented for the first time at the International Liver Congress 2013 provide new rationale for an old and established treatment option for portal hypertension. Additionally, spleen stiffness predicts the occurrence of clinical complications, which is of paramount importance in clinical practice. In patients with cirrhosis, increasing blood pressure in the abdominal circulatory system (known as portal hypertension) leads to potentially lethal complications...

2011-03-15 15:39:00

Budd-Chiari syndrome (BCS) results from hepatic venous outflow obstruction at any level from hepatic venules to the right atrium. Few patients respond to medical treatment (anticoagulation ± thrombolytic therapy, diuretics). However, most patients need intervention to restore the hepatic blood flow. Restoring outflow in one of the major hepatic veins by balloon dilatation ± stenting is the management of choice. When not possible or failed,...

2010-09-22 13:49:18

Hyponatremia may lead to neurological complications A new study published in the October issue of the journal Hepatology found that patients with severe portal-hypertensive bleeding who are treated with terlipressin may experience an acute reduction of sodium in their blood. This reduction in serum sodium, known as hyponatremia, can cause adverse reactions such as neurological complications, and is rapidly reversible upon terlipressin withdrawal. Researchers suggest that serum sodium should...

2010-06-09 21:32:33

Adverse events increase when ligation is combined with nadolol A controlled trial conducted by researchers at the E-DA Hospital in Kaohsiung, Taiwan, suggests that a combination of band ligation and nadolol may not be the most effective prophylaxis for first variceal bleeding resulting from cirrhosis. Results of this study appear in the July issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD). Esophageal...

2010-05-25 13:38:01

Study shows sustained virologic response prevents EV Italian researchers have discovered that antiviral treatment and sustained virologic response (SVR) prevents esophageal varices in patients with compensated hepatitis C (HCV)-induced cirrhosis, indicating that endoscopic surveillance can be safely delayed or avoided in these patients. Full findings are published in the June issue of Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD). According to the...

2010-04-27 14:09:18

Presence and type of complications predictors of mortality A recent study by Danish researchers discovered patients with alcoholic cirrhosis had a high prevalence of complications at the time of the disease diagnosis. Researchers noted that complications, such as ascites (excessive fluid in the abdomen), were predictors of mortality, but did not develop in a predictable sequence. Results of this 12-year mortality study appear in the May issue of Hepatology, a journal published by...

2010-04-20 09:20:15

Neural vasoregulation represents a rapid and potent mode of altering vascular tone but has not been investigated thoroughly during portal hypertension. Heat shock protein-90 (HSP-90) is well-known to act as a molecular chaperone optimizing endothelial and neural NO-synthase (eNOS, nNOS) enzyme activity and thus, NO production. Although HSP-90 has been shown to mediate in large parts the enhanced eNOS-dependent NO overproduction in the splanchnic circulation during portal hypertension, it is...

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2010-04-15 14:39:45

Doctors could soon be prescribing a dose of dark chocolate to help patients suffering from liver cirrhosis and from dangerously high blood pressure in their abdomen, according to new research presented today at the International Liver CongressTM 2010, the Annual Meeting of the European Association for the Study of Liver in Vienna, Austria. According to the Spanish research, eating dark chocolate reduces damage to the blood vessels of cirrhotic patients and also lowers blood pressure in the...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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