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Latest Poxviridae Stories

2006-01-24 10:24:31

WASHINGTON (Reuters) - Chimpanzee blood may be used to provide a safer vaccine against smallpox, U.S. researchers reported on Monday. A vaccine made by splicing chimp and human antibodies was both safer and more effective than the current vaccine, which uses a live virus and has a high rate of side effects, researchers reported. "This is an important finding in the race to develop effective measures against a potential bioterror attack involving the deadly smallpox virus," said Dr....

2006-01-23 18:20:51

WASHINGTON (Reuters) - Chimpanzee blood may provide a safer vaccine against smallpox, U.S. researchers reported on Monday. A vaccine made by splicing chimp and human antibodies was both safer and more effective than the current vaccine, which uses a live virus and has a high rate of side effects, the researchers reported. "This is an important finding in the race to develop effective measures against a potential bioterror attack involving the deadly smallpox virus," said Dr. Elias...

2006-01-23 18:20:00

WASHINGTON (Reuters) - Chimpanzee blood may provide a safer vaccine against smallpox, U.S. researchers reported on Monday. A vaccine made by splicing chimp and human antibodies was both safer and more effective than the current vaccine, which uses a live virus and has a high rate of side effects, the researchers reported. "This is an important finding in the race to develop effective measures against a potential bioterror attack involving the deadly smallpox virus," said Dr. Elias Zerhouni,...

2005-12-07 17:59:09

NEW YORK (Reuters Health) - About three quarters of patients with monkeypox have affected lymph nodes, a condition that is rare in cases of smallpox or chicken pox, investigators report in two articles in the journal Clinical Infectious Diseases. Other common features of monkeypox, in addition to rash and fever, include chills, sore throat, headache and muscle pain. Considered a possible agent of bioterrorism, it is important to recognize signs and symptoms of monkeypox and to...

2005-10-18 22:26:10

WINSTON-SALEM, N.C. "“ Children who have been treated with steroids and are exposed to chicken pox tend to have a more severe case of the virus, according to pediatric oncologists at Brenner Children's Hospital, part of Wake Forest University Baptist Medical Center. New research published in the October issue of Pediatrics, says that children who are undergoing steroid treatments for diseases like childhood leukemia are at increased risk of contracting a more severe form of chicken...

2005-08-09 18:41:58

PORTLAND, Ore. -- Researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University have developed new diagnostic methods to better detect future monkeypox or smallpox outbreaks. The research also sheds new light on the 2003 monkeypox outbreak in the Midwest -- monkeypox is closely related to smallpox. This new information suggests that the 2003 outbreak was larger than the 72 cases reported by the Centers for Disease Control and Prevention (CDC). The...

2005-07-18 04:43:09

ST. LOUIS -- An outbreak of 72 cases of monkeypox in the United States during the summer of 2003 didn't produce a single fatality, even though the disease usually kills 10 percent of those infected. Why did none of the patients die? New research from Saint Louis University Health Sciences Center and several partner institutions may provide an answer. In this month's issue of Virology, researcher and senior author Mark Buller, Ph.D., from Saint Louis University Health Sciences Center and...

2005-06-27 17:13:16

WASHINGTON (Reuters) - A cancer pill noted for itseffectiveness in stopping leukemia in some patients can alsohelp delay the deadliest effects of a pox virus in mice --offering the prospect of using similar drugs to treat orprevent smallpox, scientists said on Monday. Tests of Gleevec, Swiss drug giant Novartis AG's successfulleukemia pill, showed it could save the lives of mice infectedwith vaccinia -- a close relative of smallpox. The drug, known generically as imatinib or STI-571,...

2005-06-27 14:32:09

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The findings, say the investigators, suggest that Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine. The classic smallpox vaccine is made from live, weakened vaccinia virus and is not...

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2005-06-27 12:28:48

WASHINGTON (Reuters) -- A cancer pill noted for its effectiveness in stopping leukemia in some patients can also help delay the deadliest effects of a pox virus in mice -- offering the prospect of using similar drugs to treat or prevent smallpox, scientists said on Monday. Tests of Gleevec, Swiss drug giant Novartis AG's successful leukemia pill, showed it could save the lives of mice infected with vaccinia -- a close relative of smallpox. The drug, known generically as imatinib or STI-571,...


Latest Poxviridae Reference Libraries

70_8c49b7354584ec16683e38a21f19f6de
2011-02-23 21:18:56

Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family. It is well-known for its role in eradicating smallpox. It was the first human disease to to successfully be eradicated by science. The World Health Organization was the one who completed the endeavor. The vaccinia virus saw renewed interest in the early 21st century due to concerns about the smallpox virus being used as an agent for bioterrorism. They can be divided into four types:...

45_024a35045beb369ed398fbeaa6dcb4d2
2011-02-23 17:00:17

The Molluscum contagiosum virus, MCV, is a virus, in the poxvirus family, that causes the disease Molluscum contagiosum in humans. The virions have a complex structure that is consistent with the structure of the poxvirus family. Since the virus cannot routinely be cultured diagnosis is made on the clinical appearance. It can be confirmed by excisional biopsy. There are four types of MCV and MCV-2 is usually seen in adults and is often sexually transmitted. Photo Copyright and Credit

45_10ad4db95d2f95cace360b9700900049
2011-01-05 13:01:59

The African Swine Fever virus, ASFV, is a double-stranded DNA virus that replicates in the cytoplasm of infected cells. It can affect most pigs, wild and domesticated, as well as soft ticks. It is the only virus with a DNA genome that is transmitted by arthropods. The virus causes a lethal hemorrhagic disease in domestic pigs which sometimes leads to death in as little as a week. In every other species the virus causes no discernible disease. The virus is endemic to Sub-Saharan Africa...

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