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Latest Primary aldosteronism Stories

Sodium Retention And Blood Pressure Increased By Common Genetic Mutation
2012-05-30 08:43:57

Nearly 40 percent of the small adrenal tumors that cause big problems with high blood pressure share a genetic mutation that causes patients to retain too much sodium, researchers report. The study of 47 human, benign adrenal gland tumors also showed a mutation of the gene KCNJ5 is twice as likely to occur in women — 71 versus 29 percent — as it points to potential new treatments for some patients who don't respond to current hypertension regimens, said Dr. William E. Rainey,...

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2011-02-11 10:25:00

High blood pressure may in some cases be caused by benign hormone-producing tumors of the adrenal cortex. A joint Swedish-American research effort has now uncovered a genetic cause behind the occurrence of such tumors. The findings were published Feb. 10 in the journal Science. Approximately 5 percent of patients with elevated blood pressure have benign endocrine tumors in their adrenal gland. The tumors produce abnormally high levels of the hormone aldosterone (the condition is known as...

2010-11-10 01:04:00

A hormone already responsible for increasing blood pressure by prompting the kidneys to retain salt appears to moonlight as a major stimulator of the brain centers that control the vascular system and blood pressure. Researchers at UT Southwestern Medical Center studied patients who overproduce aldosterone to see whether the hormone had any effect on sympathetic nerve activity responsible for blood pressure increases. "Between 10 percent and 20 percent of patients with high blood pressure who...

2009-06-04 22:18:50

Despite having normal blood pressure, U.S. researchers say overweight male teens show signs of heart damage. Researchers at the Medical College of Georgia in Augusta looked at 126 healthy 15- to 17-year-old students in a local high school and found overweight males showed elevated levels of the hormone aldosterone. This hormone produced by the adrenal gland is known to increase sodium, water retention and blood pressure. The researchers suggest the overweight males' thickened heart walls...

2008-02-13 03:00:13

By Timonera, Elizabeth R Paiva, Maria Emilia; Lopes, Jose Manuel; Eloy, Catarina; van der Kwast, Theodore; Asa, Sylvia L Adenomatoid tumor and myelolipoma are benign, hormonally inactive tumors that are often incidental findings in the adrenal glands. Myelolipoma is more common than adenomatoid tumor in this location but both are rare, and as yet, the pathogenesis of both remains unclear.We report 2 cases of composite adenomatoid tumor and myelolipo-ma, incidentally found in the adrenal...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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