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Latest prions Stories

2011-12-01 11:11:07

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature. Findings published this month in the peer-reviewed journal, Public Library of Science (PLoS) Pathogens, demonstrate that up to seven months before an animal shows physical signs of having a prion infection, a particular prion protein in the brain was being eradicated. This member of the prion family is known...

2011-10-04 10:47:20

The brain damage that characterizes Alzheimer's disease may originate in a form similar to that of infectious prion diseases such as bovine spongiform encephalopathy (mad cow) and Creutzfeldt-Jakob, according to newly published research by The University of Texas Health Science Center at Houston (UTHealth). "Our findings open the possibility that some of the sporadic Alzheimer's cases may arise from an infectious process, which occurs with other neurological diseases such as mad cow and...

2011-09-14 22:24:56

Finding opens possibility of treating brain-wasting mad cow disease In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases. The researchers, led by Thomas Wisniewski, MD, professor of neurology, pathology and psychiatry, report their findings in today's online...

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2011-08-21 14:47:01

Children who received pituitary growth hormone treatments after 1977, when scientists started purifying them, are less likely to develop Creutzfeldt - Jakob disease (CJD) than those who received earlier, unpurified treatments, a team of researchers has discovered. The authors of the study, which was published in The Journal of Clinical Endocrinology & Metabolism (JCEM) earlier this month, were looking to provide updated CJD information to prior U.S. National Hormone and Pituitary...

2011-08-09 08:03:20

A person's ability to battle viruses at the cellular level remarkably resembles the way deadly infectious agents called prions misfold and cluster native proteins to cause disease, UT Southwestern Medical Center researchers report. This study marks the first discovery of so-called "good" prion-like proteins in human cells and the first to find such proteins involved in innate immunity: the way the body recognizes and responds to threats from viruses or other external agents, said Dr. Zhijian...

2011-08-08 13:24:00

Maryland CWD Containment Area added to list of states impacted by Pennsylvania's parts ban HARRISBURG, Pa., Aug. 8, 2011 /PRNewswire-USNewswire/ -- With thousands of Pennsylvania hunters heading off to hunt big game in other states and Canadian provinces, Pennsylvania Game Commission Executive Director Carl G. Roe reminds hunters that, in an effort to prevent the introduction of Chronic Wasting Disease (CWD) into the Commonwealth, the agency prohibits hunters from importing specific...

2011-07-25 13:29:02

It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals. Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of "seed" to get started. Biochemists at Emory University School of Medicine have identified a yeast protein called Lsb2...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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