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Latest prions Stories

2009-11-18 13:51:04

May Promote Prion-Dependent Diseases The regulating protein Srebp2 drives cholesterol formation, which prions need for their propagation, in prion-infected neuronal cells. With these findings, published in the current issue of the Journal of Biological Chemistry, scientists of Helmholtz Zentrum Mnchen and Technische Universität Mnchen anticipate new approaches in drug development to combat prion infection. Prions are causing fatal and infectious diseases of the nervous system, such as...

2009-10-14 13:17:08

Specific cells within the immune system could help explain why younger people are more susceptible to variant CJD, scientists believe Specific cells within the immune system could help explain why younger people are more susceptible to variant CJD, scientists believe. Patients diagnosed with variant CJD are, on average, 28 years old but it has been unclear why older people are not as affected by the disease. Research at The Roslin Institute of the University of Edinburgh has identified...

2009-10-06 07:50:42

A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions and the closest synthetic analogs that scientists have created in the lab. Prions are the infectious proteins responsible for human Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, or "mad cow"...

2009-09-29 13:14:42

A University of Toronto-led team of scientists says it has determined the evolutionary origin of the prion gene. The researchers said the diseased prion proteins are responsible for the fatal neurodegenerative Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy, also known as mad cow disease, as well as scrapie and chronic wasting disease in livestock. The scientists said their findings hold promise for efforts to reveal the physiological function of members of the prion...

2009-09-28 15:31:24

A University of Toronto-led team has uncovered the evolutionary ancestry of the prion gene, which may reveal new understandings of how the prion protein causes diseases such as bovine spongiform encephalopathy (BSE), also known as "mad cow disease." Diseased prion proteins are responsible for the fatal neurodegenerative Creutzfeldt-Jakob disease (CJD) in humans, and BSE, scrapie and chronic wasting disease (CWD) in livestock. Overall, this work holds promise for efforts to reveal the...

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2009-09-10 07:38:02

According to a study published on Wednesday, it appears that a variety of prion disease found in deer may be spread through the fecal matter of infected animals even when they exhibit no symptoms of the illness.  Researchers say that their finds on the deadly brain disorder known as chronic wasting disease (CWD)"”a close cousin of the infamous mad-cow disease"”may have significant ramifications for farmers. The research was led by Nobel laureate Stanley Prusiner at the...

2009-08-19 11:06:03

A British expert on the human form of mad cow disease says it is essential that coroners test the brains and spleens of all young people who die. Professor John Collinge says without post-mortem tests for the infection it is impossible to get accurate information on how many people in Britain may be carrying it, The Times of London reported Wednesday. Collinge, a member of a government panel monitoring the progress of spongiform encephalopathy, or mad cow disease, says systematic testing is...

2009-07-30 11:54:05

Data from an ongoing multi-year study suggest that people who consume deer and elk with chronic wasting disease (CWD) may be protected from infection by an inability of the CWD infectious agent to spread to people. The results to date show that 14 cynomolgus macaques exposed orally or intracerebrally to CWD remain healthy and symptom free after more than six years of observation, though the direct relevance to people is not definitive and remains under study. Cynomolgus macaques often are...

2009-06-25 14:09:59

North Carolina State University researchers have discovered a link between copper and the normal functioning of prion proteins, which are associated with transmissible spongiform encephalopathy diseases such as Cruetzfeldt-Jakob in humans or "mad cow" disease in cattle. Their work could have implications for patients suffering from these diseases, as well as from other prion-related diseases such as Alzheimers or Parkinson's.Prion proteins, or PrPs, are commonly found in brain tissue and...

2009-06-23 14:37:00

HARRISBURG, Pa., June 23 /PRNewswire-USNewswire/ -- The Pennsylvania Game Commission has posted the 2009 Citizen Advisory Committee (CAC) reports, including their recommendations for deer population changes, on the agency's website. Five CACs were conducted in 2009 in Wildlife Management Units (WMUs) 1A, 2E, 3A, 4A and 5B. To view the reports, visit the Game Commission's website (www.pgc.state.pa.us), click on "White-Tailed Deer" icon in the center of the homepage, select "Citizen Advisory...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.