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Latest Prodrugs Stories

2012-11-30 08:24:39

WOODCLIFF LAKE, N.J., Nov. 30, 2012 /PRNewswire/ -- Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted for priority review Eisai's New Drug Application (NDA) for AcipHex® Delayed-Release Sprinkle Capsules 5mg and 10mg for the proposed indication of healing of Gastroesophageal Reflux Disease (GERD), maintenance of healing of GERD and improvement of symptoms of GERD in children 1 to 11 years of age. (Logo:...

2012-11-16 08:23:38

PARIS and TARRYTOWN, N.Y., Nov. 16, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion and recommended the granting of marketing authorization for ZALTRAP(®) (ziv-aflibercept) Injection for Intravenous Infusion in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI)...

2012-11-05 08:32:54

BARCELONA, Spain, November 5, 2012 /PRNewswire/ -- Life Science Entrepreneurs S.L.U., a company dedicated to the early-stage development of high-risk/very high return ventures, announced today the conclusion of a first investment for an antiplatelet drug candidate code-named NmC. Private investors from Barcelona, Geneva and Basel, all active in medical applications of life sciences, have funded the assays to confirm the safety and efficacy of the cardiovascular drug NmC....

2012-11-05 08:24:25

DALLAS, November 5, 2012 /PRNewswire/ -- RnRMarketResearch.com adds "1,4-Butanediol Market, By Application & Geography, Trends & Forecasts to 2017" report to its store. The report says global BDO market is estimated to reach 2,548.5 kilo tons by 2017, growing at a CAGR of 5.5% from 2012 to 2017. Asia-Pacific is leading accounting for more than 55% of total volume consumed in 2011 ROW market for BDO is expected to advance at rapid pace during the next few years and...

2012-11-02 14:50:28

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease. Xiaoting Zhang, PhD, and his colleagues have identified a specific estrogen receptor co-activator–known as MED1–as playing a central role in mediating tamoxifen resistance...

2012-10-29 07:21:51

DALLAS, October 29, 2012 /PRNewswire/ -- The report "1, 4-butanediol Market By Technology (Reppe Process, Davy process, Butadiene Process, Propylene Oxide Process & Others), Applications, & Geography: Global Industry Trends & Forecasts to 2017", published by MarketsandMarkets ( http://www.marketsandmarkets.com), defines and segments the global 1,4-butanediol market by products with analysis and forecasting of the global volume and revenue. As of year 2012,...

2012-10-09 15:25:00

PITTSBURGH, Oct. 9, 2012 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that it has entered into a settlement agreement with Shionogi Inc. and CIMA Labs Inc. that will resolve patent litigation related to Prednisolone Sodium Phosphate Orally Disintegrating Tablets (ODT), 10 mg, 15 mg and 30 mg. Prednisolone Sodium Phosphate ODT is the generic version of Shionogi's Orapred ODT(®), which is indicated for the treatment of certain pulmonary diseases such as asthma. Additionally, the...

2012-08-30 10:24:03

NIH study also shows that overall stroke risk is down from 10 years ago Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health. Lacunar strokes occur due to chronic high blood pressure and typically produce small lesions deep within the brain....

2012-08-29 07:53:39

The findings were presented by Dr Jolanta Siller-Matula from Medical University of Vienna Standard antiplatelet treatment in patients undergoing percutaneous coronary intervention (PCI) consists of a dual antiplatelet therapy with aspirin and an ADP receptor inhibitor such as clopidogrel. But measurements of platelet aggregation in clopidogrel treated patients indicate that one patient in four is a non-responder to the drug. Such non-responsiveness is attributed to clopidogrel's...

2012-08-29 07:27:28

Lifelong anticoagulation is necessary for the prevention of stroke in patients with rhythm disturbances and with mechanical valves. Patients who have a coronary stent implanted also need the antiplatelet drugs aspirin and clopidogrel to prevent the rare but lethal complication of stent thrombosis. For patients taking oral anticoagulant drugs (for atrial fibrillation or mechanical valve) who also have to undergo coronary stenting, the optimal antithrombotic treatment is still unknown, even...