Quantcast
Last updated on April 18, 2014 at 21:21 EDT

Latest Progeria Stories

2013-10-10 16:25:31

In an effort to raise $1 million, Robert Kraft will match public contributions to Foundation from now until October 23, the 17(th) birthday of LIFE ACCORDING TO SAM subject, Sam Berns. NEW YORK, Oct. 10, 2013 /PRNewswire-USNewswire/ -- Inspired at a screening of a new HBO Documentary film, LIFE ACCORDING TO SAM, the Chairman and CEO of the NFL's New England Patriots on Tuesday pledged up to half a million dollars to the Progeria Research Foundation and a clinical trial that could...

2013-04-25 20:37:23

A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging. The findings demonstrate that aspects of photoaging, the process of skin aging by chronic exposure to ultraviolet radiation, could be linked to genetic factors that accelerate the aging process when induced by the environment. The study, published in the Journal of Investigative Dermatology,...

2012-09-26 13:11:29

ASCB posts background on basic biology discoveries behind Boston Children's clinical trial reporting significant slowing of rare rapid aging disorder in children The good news widely reported this morning of positive results from a clinical drug trial at Boston Children's Hospital for the previously "untreatable" rapid aging disorder in children known as progeria has its scientific roots in basic biology discoveries made in recent years. A paper published Monday in the Proceedings of...

2012-09-24 10:25:57

Drug Originally Developed for Cancer Proves Effective for Children with Progeria BOSTON, Sept. 24, 2012 /PRNewswire-USNewswire/ -- Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. The clinical trial results, completed only six years after scientists identified the cause of Progeria, included significant improvements...

2012-04-30 00:20:05

Singapore, Apr 30, 2012 - (ACN Newswire) - Scientists have discovered that they can dramatically increase the life span of mice with progeria (premature ageing disease) and heart disease (caused by Emery-Dreifuss muscular dystrophy) by reducing levels of a protein called SUN1. This research was done by A*STAR's Institute of Medical Biology (IMB) in collaboration with their partners at the National Institute of Allergy and Infectious Diseases in the United States and the Institute of Cellular...

2012-01-03 13:05:19

Mice bred to age too quickly seemed to have sipped from the fountain of youth after scientists at the University of Pittsburgh School of Medicine injected them with stem cell-like progenitor cells derived from the muscle of young, healthy animals. Instead of becoming infirm and dying early as untreated mice did, animals that got the stem/progenitor cells improved their health and lived two to three times longer than expected, according to findings published in the Jan. 3 edition of Nature...

2011-11-02 08:52:13

Researchers have identified a potential drug therapy for a premature ageing disease that affects children causing them to age up to eight times as fast as the usual rate. The study is the first to outline how to limit and repair DNA damage defects in cells and could provide a model for understanding processes that cause us to age. The findings could have significant benefits, such as reducing degeneration of some tissues in older age, and could assist health management in countries,...

2011-10-03 19:55:01

A factor that is crucial for the proper positioning of genes in the cell nucleus has been discovered by a team of researchers from the Alexander Silberman Institute of Life Sciences at the Hebrew University of Jerusalem and the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland. The researchers found that the lamin filamentous network is an essential element in this proper positioning, the lack of which can cause specific diseases. Lamin proteins make filaments that...

2011-09-14 22:11:45

Pulling the tail of mutated protein could help illuminate problems with misfolding Researchers at MIT and Carnegie Mellon University are using both civil engineering and bioengineering approaches to study the behavior of a protein associated with progeria, a rare disorder in children that causes extremely rapid aging and usually ends in death from cardiovascular disease before age 16. The disease is marked by the deletion of 50 amino acids near the end of the lamin A protein, which helps...

b1c1be76beeda9b7cfcf58a73b7ce5e8
2011-06-30 12:30:00

Scientists have discovered a drug they believe can reverse the effects of premature aging and could extend human life by over a decade. Rapamycin was created from a chemical found in the soil on Easter Island, which is one of the most remote places on Earth and 2,000 miles off the coast of Chile. The drug, which has been nicknamed the "forever young" drug, was used in experiments on children suffering from Hutchinson-Gilford Progeria Syndrome (HGPS).  HGPS is a rare condition in which...