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Latest Prostate-specific antigen Stories

Obesity Linked To Increased Risk Of Prostate Cancer
2013-04-24 09:24:35

redOrbit Staff & Wire Reports - Your Universe Online Researchers from the Columbia University Mailman School of Public Health have discovered that benign precancerous lesions detected in prostate biopsies are more likely to develop into prostate cancer for obese men compared to their normal-weight counterparts. Writing in the online edition of the journal Cancer Epidemiology, Biomarkers & Prevention, study author and associate professor of epidemiology Andrew Rundle and...

2013-04-17 14:35:17

A new design of screening could improve ratio between benefit and harms of screening Focusing prostate cancer testing on men at highest risk of developing the disease is likely to improve the ratio between benefits and the harms of screening, suggests a paper published today on bmj.com. Prostate specific antigen (PSA) screening is widely used for the early detection of prostate cancer, but remains highly controversial, as it became widespread long before evidence to prove its value....

2013-04-15 14:05:31

Technique relies on correcting for genetic variants Genetic variants have been identified which can increase serum prostate specific antigen (PSA) concentrations and prostate cancer risk. A new study published in The Journal of Urology® reports that correcting PSA levels for these genetic variants can have significant consequences, including avoiding unnecessary biopsies for some men and eliminating false complacency for others. In this study of 964 healthy Caucasian men, correcting...

2013-04-09 11:39:10

Shared-decision making, clear patient preference recommended before PSA testing Men between the ages of 50 and 69 should discuss the limited benefits and substantial harms of the prostate-specific antigen (PSA) test with their doctor before undergoing screening for prostate cancer, according to new recommendations issued today by the American College of Physicians (ACP). "Screening for Prostate Cancer: A Guidance Statement from the American College of Physicians" appears in the April 9...

2013-04-05 13:04:52

Non-invasive 'liquid biopsies' can find metastatic or recurrent prostate cancer, in a low cost assay suitable for most healthcare systems, finds research published in BioMed Central's open access journal Genome Medicine. Genomic signatures of prostate cancer, isolated from plasma DNA, display abnormal copy numbers of specific areas of chromosomes. It is even possible to separate out patients who develop resistance against hormone deprivation therapy, which is the most common form of treatment...

2013-04-04 12:16:56

Despite menopause-like side effects, continuous hormone treatment is superior to intermittent therapy A study published today in the New England Journal of Medicine recommends a dramatic shift in the way doctors treat metastatic prostate cancer. "These results have changed the way I treat patients," said Ian M. Thompson Jr., M.D., director of the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio and senior author on the international...

2013-03-18 20:59:04

The digital rectal exam is an important screening test that can discover prostate cancer that a prostate-specific antigen or PSA test may not, despite the higher sensitivity of the PSA test, according to Penn State College of Medicine researchers. The digital rectal examination is a procedure where a physician feels the surface of the prostate with a gloved finger. The doctor is able to feel any lumps or hard areas on the prostate. A PSA test checks for levels of prostate-specific...

2013-03-18 11:12:57

Men who participate in biennial PSA based screening have a lower risk of being diagnosed as well as dying from prostate cancer up to 9 years after their last PSA test, according to the results of a new study to be presented at the 28th Annual EAU Congress in Milan A joint Swedish-UK study aimed to examined the risk of developing prostate cancer after last invitation to screening. This investigation follows up on previous publication from the Göteborg randomized screening trial...

2013-03-18 11:08:57

A genetic score based on PCa risk-associated single nucleotide polymorphisms (SNPs) is an independent predictor of prostate biopsy outcomes, suggest the results of a new study conducted by a group from the Department of Urology Huashan Hospital, Fudan University in Shanghai, China. The authors, who relate their findings to the male population in China, also suggest that this score can improve predictive performance of existing clinical variables, especially for patients with a total PSA...


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