Quantcast
Last updated on April 18, 2014 at 12:48 EDT

Latest Protease inhibitor Stories

2006-07-19 00:05:07

By Karla Gale NEW YORK (Reuters Health) - Knowledge of available treatment options and the significance of drug resistance has declined in patients infected with HIV, the virus that causes AIDS, according to results of a survey presented Tuesday. "In the early days of HIV, patients often understood the science of HIV as much as most clinicians," Dr. Howard Grossman told Reuters Health. "But once the complex drug regimens with HAART (highly active antiretroviral therapy) came out, and...

2006-07-18 23:54:27

By Karla Gale NEW YORK (Reuters Health) - Knowledge of available treatment options and the significance of drug resistance has declined in patients infected with HIV, the virus that causes AIDS, according to results of a survey presented Tuesday. "In the early days of HIV, patients often understood the science of HIV as much as most clinicians," Dr. Howard Grossman told Reuters Health. "But once the complex drug regimens with HAART (highly active antiretroviral therapy) came out, and...

2006-02-15 09:48:54

CHICAGO (Reuters) - Bristol-Myers Squibb on Wednesday said it cut a deal with two generic drugmakers to allow cheap versions of its newest AIDS drug to be made in sub-Saharan Africa and India, where millions suffer from the disease. Bristol-Myers said it will license and lend technical expertise for its drug Reyataz to generic manufacturers Aspen PharmaCare of South Africa and Emcure Pharmaceuticals of India. Reyataz is a once-daily protease inhibitor, a second-line treatment for...

2005-06-02 01:45:00

The immunodeficiency that arises in HIV may be due to excessive programmed cell death of immune CD4 T cells. HIV protease inhibitors (PI) can block programmed cell death in virus-infected T cells in vitro, but have also been shown to induce programmed cell death at higher concentrations. The mechanisms for these paradoxical data are unclear, as is whether PI therapy would aid CD4 T cell reconstitution in HIV patients in vivo. In a study appearing online on June 2 in advance of the print...