Latest Protease Stories
Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source.
Protease inhibitor drugs are one of the major weapons in the fight against HIV, the virus that causes AIDS, but their effectiveness is limited as the virus mutates and develops resistance to the drugs over time.
A molecule that lies dormant until it encounters a cancer cell, then suddenly activates and rouses the bodyâ€™s immune system to fight cancer cells directly, marks the latest step in scientistsâ€™ efforts to tap the bodyâ€™s own resources to fight the disease.
Virtually all processes in the human body rely on a unique class of proteins known as enzymes.
Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually result in the development of new drugs to treat cancer and other illnesses.
With the number of norovirus infection cases rising across the country, scientists from the University of Southampton have successfully crystallized a key norovirus enzyme, which could help in the development of a norovirus treatment.