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Latest Protease Stories

2010-02-04 11:50:24

Novel therapies could improve potency of existing AIDS treatments, help to combat drug-resistant virus strains A team of scientists at The Scripps Research Institute has identified two compounds that act on novel binding sites for an enzyme used by the human immunodeficiency virus (HIV), the virus that causes AIDS. The discovery lays the foundation for the development of a new class of anti-HIV drugs to enhance existing therapies, treat drug-resistant strains of the disease, and slow the...

2010-02-03 15:50:46

Many favorite breakfast cereals, candies, beers, and other foods and beverages owe much of their smooth, delicious flavor to malt. Malting barleys--the source of that malt--are the focus of studies at the Agricultural Research Service's (ARS) malting barley laboratory in Madison, Wis., part of the Cereal Crops Research Unit. There, chemist Mark Schmitt and plant physiologist Allen Budde are discovering more about what goes on inside barley grains as they germinate, or sprout, in the malt...

2009-10-29 15:01:00

BRISBANE, Calif., Oct. 29 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) today announced that Dan Welch, Chairman, Chief Executive Officer and President of InterMune, will present at the Oppenheimer 20th Annual Healthcare Conference in New York on November 4, 2009 at 3:20 p.m. EST. To access a live audio webcast of the presentation, investors and other interested parties may log on to the investor relations page of InterMune's corporate website at www.intermune.com. The company...

2009-10-29 06:00:00

BRISBANE, Calif., Oct. 29 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) announced today that it will release third quarter 2009 financial results on Thursday, November 5, 2009 at 4:00 p.m. Eastern time. A live conference call and webcast will be hosted by InterMune at 4:30 p.m. Eastern time that same day. To access the live teleconference, dial 888-799-0528 (U.S.) or 973-200-3372 (international), conference ID# 37626791. To access the webcast, please log on to the company's...

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2009-10-16 13:50:43

Researchers have solved the mystery of how barnacles attach themselves to other objects, showing that barnacle glue binds together exactly the same way as human blood does when it clots, BBC News reported. Barnacles are crustaceans that live in shallow ocean environments. As larvae they affix to hard substrates, then remain stationary for the rest of their lives. The barnacles secrete an adhesive substance in order to attach themselves to a surface. Scientists have long been aware of the...

2009-10-01 06:00:00

BRISBANE, Calif., Oct. 1 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) today announced that Dan Welch, Chairman, Chief Executive Officer and President of InterMune, will present at the Fourth Annual JMP Securities Healthcare Focus Conference in New York on October 5, 2009 at 3:30 p.m. EDT. To access a live audio webcast of the presentation, investors and other interested parties may log on to the investor relations page of InterMune's corporate website at www.intermune.com....

2009-09-21 13:47:42

Caspase-3 Cleaves in Unforeseen Ways Investigators at Burnham Institute for Medical Research (Burnham) have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called N-terminomics, Guy Salvesen, Ph.D., professor and director of the Apoptosis and Cell Death Research program of Burnham's NCI-designated Cancer Center, and colleagues determined the cleavage sites on target proteins and found,...

2009-09-07 06:43:08

UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human infants. The findings offer a proof-of-principle, at least in mice, that the genetic equivalent to human lissencephaly, also known as "smooth brain"...

2009-07-30 11:10:07

UCSF researchers have identified a new potential drug target for the herpes virus that causes Kaposi's sarcoma, re-opening the possibility of using the class of drugs called protease inhibitors against the full herpes family of viruses, which for 20 years has been deemed too difficult to attain.The new drug target, which is known as a protease dimer, could serve as a model for developing new therapeutics for diseases ranging from cancer to Alzheimer's, the researchers say. Findings are...

2009-07-29 15:00:00

BRISBANE, Calif., July 29 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) announced today that it will release second quarter 2009 financial results on Thursday, August 6, 2009 at 4:00 p.m. Eastern time. A live conference call and webcast will be hosted by InterMune at 4:30 p.m. Eastern time that same day. To access the live teleconference, dial 888-799-0528 (U.S.) or 973-200-3372 (international), conference ID# 22196018. To access the webcast, please log on to the company's...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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