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Last updated on April 16, 2014 at 4:54 EDT

Latest Proteasome Stories

2010-12-06 15:00:00

EMERYVILLE, Calif., Dec. 6, 2010 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will host an investor teleconference and webcast. Investigators will discuss data presentations surrounding carfilzomib in multiple myeloma, as featured at the 52nd American Society of Hematology (ASH) Annual Meeting and Exposition in Orlando, Florida. The virtual event will begin at 10:00 a.m. ET on December 7, 2010. The live webcast will be available at:...

2010-11-10 15:00:00

EMERYVILLE, Calif., Nov. 10, 2010 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at the Lazard Capital Markets 7th Annual Healthcare Conference on Wednesday, November 17, 2010 at 10:30 a.m. Eastern Time (7:30 a.m. Pacific Time). Interested parties may access a live webcast of the presentation on our website at: http://www.onyx-pharm.com/view.cfm/32/Event-Calendar It is recommended that listeners log on 15 minutes early in order to...

2010-11-04 15:00:00

EMERYVILLE, Calif., Nov. 4, 2010 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at the Credit Suisse 2010 Healthcare Conference on Thursday, November 11, 2010 at 9:00 a.m. Mountain Time (8:00 a.m. Pacific Time). Interested parties may access a live webcast of the presentation on our website at: http://www.onyx-pharm.com/view.cfm/32/Event-Calendar It is recommended that listeners log on 15 minutes early in order to register and download any...

2010-11-04 01:11:55

Proteasome inhibitor reduces inflammation and promotes bone healing in arthritis models A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis (RA). In this study, bortezomib displayed favorable effects in an animal model of inflammatory arthritis that mimics RA, in reducing disease severity and inflammation, and promoting...

2010-10-18 12:51:36

Interaction between 'kiss of death' marker and protein-chopping factory -- new target for anti-TB drugs Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Stony Brook University have discovered a key difference in the way human cells and Mycobacterium tuberculosis bacteria, which cause TB, deliver unwanted proteins "” marked with a "kiss of death" sequence "” to their respective cellular recycling factories. This critical difference, described...

2010-09-23 08:00:00

BURLINGTON, Mass., Sept. 23 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, for the treatment of multiple myeloma, more surveyed European hematologist-oncologists consider the combination of immunomodulatory agents and proteasome inhibitors promising with respect to efficacy than is the case for any other drug regimen combinations. In light of these findings, the emerging regimen of Onyx...

2010-09-16 15:00:00

EMERYVILLE, Calif., Sept. 16 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it will present at the UBS Global Life Sciences Conference on Wednesday, September 22, 2010 at 3:00 p.m. Eastern Time (12:00 p.m. Pacific Time). Interested parties may access a live webcast of the presentation on our website at: http://www.onyx-pharm.com/view.cfm/32/Event-Calendar It is recommended that listeners log on 15 minutes early in order to register and download any...

2010-09-09 01:15:06

Scientists have discovered a small molecule that helps human cells get rid of the misfolded, disfigured proteins implicated in Alzheimer´s disease and other neurodegenerative ailments. This potential drug could have applications for other conditions as well. Cells create and discard proteins continuously, a process that relies on a balance between the speed with which new proteins are created and damaged ones destroyed. Protein destruction occurs through a sophisticated...

2010-09-08 14:33:42

Discovery reveals a natural mechanism for getting rid of excess amyloid Chemists at the University of California, San Diego, have identified how a protein that accumulates in the brains of people with Alzheimer's disease interferes with the ability of cells to get rid of debris. They also found a natural mechanism by which this protein, amyloid beta, itself may be discarded. Plaques of amyloid are a hallmark of the ailment, but no one is sure exactly how they contribute to catastrophic loss...

2010-09-08 02:00:00

EMERYVILLE, Calif., Sept. 8 /PRNewswire-FirstCall/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it has entered into an exclusive agreement with Ono Pharmaceutical Co., Ltd. to develop and commercialize two compounds from Onyx's proteasome inhibitor development program, carfilzomib and ONX 0912. Under the terms of the agreement, Ono has exclusive rights to develop and commercialize both compounds for all oncology indications in Japan. Onyx retains commercialization...