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Latest Protective autoimmunity Stories

New Therapeutic Option Derived From Cord Blood Cells
2012-07-16 15:02:22

Protocol may open new avenues for cell-replacement therapies for neurological conditions For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases. Now, scientists at the Salk Institute for Biological Studies have found a new way-using a single protein, known as a transcription factor-to convert cord blood (CB) cells...

2012-03-15 05:39:01

(Ivanhoe Newswire)– Pill for spinal injury? A new study shows an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). Researchers uncover how a new pill that has shown positive results in mice with multiple sclerosis suffering from deterioration of the spinal cord, may help humans. Aside from the initial tissue damage, a great deal of the degradation of the spinal cord in SCI is...

2011-12-23 10:17:41

A research team led by Glenn Rall at the Fox Chase Cancer Center in Philadelphia, PA developed a novel mouse model to show that a fatal central nervous system (CNS) disease can be caused by a pathogen that does not replicate in the CNS. The results of this new study are published December 22nd in the Open Access journal PLoS Pathogens. The authors found that the immune response induced in response to a peripheral viral infection can be "mis-recruited" to the brain, where these activated...

2011-11-28 15:08:44

The immune system possesses a type of cell that can be activated by tissues within the body to remind the immune system not to attack our own molecules, cells and organs, UCSF researchers have discovered. The discovery is likely to lead to new strategies for fighting a range of autoimmune diseases — in which the immune system attacks and harms specific molecules and cells within us — as well as for preventing transplant rejection, according to UCSF researchers who report their...

2011-10-11 20:20:20

The research shows that in addition to the major histocompatibility complex (MHC) molecules, which present the antigen vaccine to the immune cells, genetic factors, that control some immune cells, influence the quality of response to vaccinations. The results could make it possible to prevent neuroinflammatory reactions, which are major obstacles preventing the use of the vaccination in humans. This study has just been published in the Journal of Immunology. Since the beginning of the 2000s,...

2011-08-04 21:42:01

Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men. The cells, a subset of immune-system B cells, make autoantibodies, which bind to and attack the body's own tissue. The researchers report in the August 4, 2011, issue of the journal Blood, that they found higher levels of these cells in elderly...

2011-07-07 20:33:05

Lesions to the brain or spinal cord rarely heal fully, which leads to permanent functional impairment. After injury to the central nervous system (CNS), neurons are lost and largely replaced by a scar often referred to as the glial scar based on its abundance of supporting glial cells. Although this process has been known to science for over a century, the function of the scar tissue has long been disputed. However, there are indications that it stabilizes the tissue and that it inhibits the...

2011-06-02 23:59:53

One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University. This may be one of the underlying mechanisms for the health benefits of green tea, which has attracted wide interest for its ability to help control inflammation, improve immune function and prevent cancer....

2011-04-25 14:18:56

Findings could lead to better diagnostics and more personalized treatment Researchers from Boston University School of Medicine (BUSM) have discovered that human proteins with an affinity for Dermatan Sulfate (DS) have the propensity to become autoantigens. In a companion article, the researchers also found that DS physically interacts with dead cells and that the resulting DS"“autoantigen complexes drive autoreactive B-1a cell responses and autoantibody production both in-vitro and in...

2011-03-07 14:07:47

Scientists from the Walter and Eliza Hall Institute have identified the key immune cell population responsible for regulating the body's immune response. The finding could have wide-ranging repercussions for the treatment of autoimmune diseases, organ transplantation and cancer, and change how the efficacy of newly developed drugs is measured. The discovery was made by Dr Erika Cretney, Dr Axel Kallies and Dr Stephen Nutt from the institute's Molecular Immunology division. It centred on a...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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