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Last updated on April 19, 2014 at 17:21 EDT

Latest Protein biosynthesis Stories

2014-04-18 14:05:01

Scientists studying the most common form of inherited mental disability—a genetic disease called “Fragile X syndrome”—have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals. In a paper that will be published in the May 8 Molecular Cell, but is being made available this week in the early online edition of the journal, the researchers show...

2014-04-01 13:16:37

Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age. These disorders are generally called "ribosomopathies." How can ribosomopathies first appear as diseases caused by too few cells, but later turn into diseases caused by too many cells? This paradox has puzzled the...

2014-03-31 23:23:41

Why do mutations in the proteins that make ribosomes cause bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age? A new University of Maryland-led study suggests these disorders, called ribosomopathies, are caused by a sequence of mistakes at the molecular level. College Park, MD (PRWEB) March 31, 2014 Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes...

2014-02-27 08:30:24

PISCATAWAY, N.J., Feb. 27, 2014 /PRNewswire/ -- GenScript, the world's largest provider of synthetic genes, has launched a new GenPlus(TM) Next-Generation Gene Synthesis service, which offers unmatched capacity and cost-efficiency for custom gene synthesis. Building upon over a decade of experience as the leading gene synthesis supplier in the US, GenScript has developed a new breakthrough technology: GenPlus(TM) Next-Generation Gene Synthesis. GenPlus(TM) combines the powers of...

2014-02-13 10:36:55

Ribosomes, the cellular machines that build proteins, are themselves made up of dozens of proteins and a few looping strands of RNA. A new study, reported in the journal Nature, offers new clues about how the ribosome, the master assembler of proteins, also assembles itself. "The ribosome has more than 50 different parts – it has the complexity of a sewing machine in terms of the number of parts," said University of Illinois physics professor Taekjip Ha, who led the research with U. of...

Mitochondrial Ribosome Deciphered
2014-01-24 13:37:28

ETH Zurich Researchers at the Swiss Federal Institute of Technology (ETH) in Zurich have deciphered the structure of part of the ribosome found in mitochondria, the power plants of the cell. The scientists were able to benefit from advancements in the field of electron microscopy and capture images of the mitochondrial ribosome at a level of resolution never achieved before. The ribosome can be thought of as a decryption device housed within the cell. It is able to decipher the genetic...

2013-11-21 08:27:31

Eloxx to focus on the discovery of small molecule therapeutics that selectively induces ribosomal read-through of premature termination codons for the treatment of nonsense genetic diseases HERZLIYA, Israel, November 21, 2013 /PRNewswire/ -- Eloxx Pharmaceuticals, Ltd. today announced the initial closing of its first round of financing with Roche (SIX: RO, ROG; OTCQX: RHHBY) and Pontifax, an Israeli VC firm leading the financing. Eloxx Pharmaceuticals is based on a...

Naked Mole Rat Longevity Perfect Proteins
2013-10-01 08:41:31

redOrbit Staff & Wire Reports - Your Universe Online Researchers from the University of Rochester believe they have discovered the secret behind the longevity of the world’s longest-lived rodent: the creatures produce better protein than other members of their order. Naked mole rats, which typically live approximately 30 years and tend to remain healthy until their final days, possess a unique mechanism for building proteins, according to a recently-published study from research...

How Rare 'Words' In Bacterial Genes Boost Protein Production
2013-09-27 07:29:50

Wyss Institute for Biologically Inspired Engineering at Harvard Scientists routinely seek to reprogram bacteria to produce proteins for drugs, biofuels and more, but they have struggled to get those bugs to follow orders. But a hidden feature of the genetic code, it turns out, could get bugs with the program. The feature controls how much of the desired protein bacteria produce, a team from the Wyss Institute for Biologically Inspired Engineering at Harvard University reported in the...

Near-optimal Genetic Code Model Created By Researchers
2013-08-29 04:15:01

redOrbit Staff & Wire Reports - Your Universe Online By creating a model of genetic code evolution, researchers have discovered new information about how RNA signaling could have developed into the “near-optimal” modern genetic code. Lead author Justin Jee, a doctoral student at NYU School of Medicine, and colleagues set out to account for the composition of the genetic code, which makes it possible for proteins to be constructed from amino acids with high specificity based on...