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Latest Protein biosynthesis Stories

2014-07-17 16:25:53

Publication in Science Unveils Novel, Diverse and Separate Biological Functions That Can Be Harnessed Therapeutically to Mediate a Wide Range of Human Disease SAN DIEGO and HONG KONG, July 17, 2014 /PRNewswire/ -- aTyr Pharma, an innovative rare disease therapeutics enterprise, and its subsidiary in Hong Kong, Pangu Biopharma (aTyr), announced the discovery of a new class of human proteins with therapeutic relevance for a wide range of diseases. The findings unveiled today in a...

2014-07-15 00:20:40

SAN DIEGO, July 14, 2014 /PRNewswire/ -- aTyr Pharma, an innovative rare disease therapeutics enterprise announced today, the scientific publication of a splice variant of a tRNA synthetase in association with a rare muscle disease. This article, published in the Journal of Biological Chemistry, demonstrated novel findings relative to Physiocrine proteins, that include extracellular functions derived from the tRNA synthetase gene family. These data further highlight the potential...

2014-06-06 10:00:13

University of Utah University of Utah researchers find that multiple silent mutations greatly impact protein translation So-called silent DNA mutations earned their title because, according to the fundamental rules of biology, they should be inconsequential. Reported on June 5 in PLOS Genetics online, University of Utah researchers experimentally proved there are frequent exceptions to the rule. The work was conducted in the bacteria, Salmonella enterica, used to study basic biological...

2014-06-06 09:56:06

PLOS YbeY is a conserved protein that is present in most bacteria. A study published on June 5th in PLOS Pathogens examines the function of YbeY in the cholera bacterium and reveals critical roles in RNA metabolism in this and other pathogenic bacteria. Graham Walker, from the Massachusetts Institute of Technology, USA, and colleagues previously studied E. coli YbeY and found that it acts as an "RNase"—a protein that deliberately and specifically cuts RNA molecules and thereby...

2014-05-23 11:13:49

DOE/Joint Genome Institute In the Lewis Carroll classic, Through the Looking Glass, Humpty Dumpty states, "When I use a word, it means just what I choose it to mean—neither more nor less." In turn, Alice (of Wonderland fame) says, "The question is, whether you can make words mean so many different things." All organisms on Earth use a genetic code, which is the language in which the building plans for proteins are specified in their DNA. It has long been assumed that there is only one...

2014-04-18 14:05:01

Scientists studying the most common form of inherited mental disability—a genetic disease called “Fragile X syndrome”—have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals. In a paper that will be published in the May 8 Molecular Cell, but is being made available this week in the early online edition of the journal, the researchers show...

2014-04-01 13:16:37

Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age. These disorders are generally called "ribosomopathies." How can ribosomopathies first appear as diseases caused by too few cells, but later turn into diseases caused by too many cells? This paradox has puzzled the...

2014-03-31 23:23:41

Why do mutations in the proteins that make ribosomes cause bone marrow failure and anemia early in life, followed by elevated cancer risk in middle age? A new University of Maryland-led study suggests these disorders, called ribosomopathies, are caused by a sequence of mistakes at the molecular level. College Park, MD (PRWEB) March 31, 2014 Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes...

2014-02-27 08:30:24

PISCATAWAY, N.J., Feb. 27, 2014 /PRNewswire/ -- GenScript, the world's largest provider of synthetic genes, has launched a new GenPlus(TM) Next-Generation Gene Synthesis service, which offers unmatched capacity and cost-efficiency for custom gene synthesis. Building upon over a decade of experience as the leading gene synthesis supplier in the US, GenScript has developed a new breakthrough technology: GenPlus(TM) Next-Generation Gene Synthesis. GenPlus(TM) combines the powers of...

2014-02-13 10:36:55

Ribosomes, the cellular machines that build proteins, are themselves made up of dozens of proteins and a few looping strands of RNA. A new study, reported in the journal Nature, offers new clues about how the ribosome, the master assembler of proteins, also assembles itself. "The ribosome has more than 50 different parts – it has the complexity of a sewing machine in terms of the number of parts," said University of Illinois physics professor Taekjip Ha, who led the research with U. of...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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