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Latest Protein domains Stories

2014-05-26 12:36:49

Ecole Polytechnique Fédérale de Lausanne Like our own bodies, cells have their own skeletons called 'cytoskeletons' and are made of proteins instead of bones. These network-like structures maintain the cell's shape, provide mechanical support, and are involved in critical processes of the cell's lifecycle. The cytoskeleton is an object of intense scientific and medical research, which often requires being able to observe it directly in cells. Ideally, this would involve...

2013-11-26 10:21:41

A new mechanism that regulates the way blood vessels grow and connect to each other has been discovered by an international team of researchers at Karolinska Institutet in Sweden, and Heinrich Heine University Düsseldorf, Germany. The knowledge might open up new opportunities for future cancer therapy. The study is published in the scientific journal PNAS. If stretched out, the blood vessels in a human body would reach more than twice around the earth. The complex circulatory system...

2013-10-24 10:23:58

A protein safeguards against cataracts The refractive power of the human eye lens relies on a densely packed mixture of proteins. Special protective proteins ensure that these proteins do not clump together as time passes. When this protective mechanism fails, the ocular lens becomes clouded – the patient develops a cataract. Scientists at the Technische Universitaet Muenchen (TUM) have now resolved the activation mechanism of one of these protective proteins, laying the foundation for...

Molecular Muscles Inside Cells Help Them Sense, Respond To Their Environments
2013-10-21 07:27:59

Johns Hopkins Medicine Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities. A summary of the discovery, published online Oct. 20 in the journal Nature Materials, specifically sheds light on how forces outside of cells are translated into internal signals. A computer model the researchers...

2013-09-23 14:00:33

Eukaryotic cells are compartmentalized by membranes, whose shape and dynamics are precisely regulated to maintain their correct functions. Consequently, many cellular processes such as endocytosis, migration and morphogenesis rely on proteins that bind directly to membranes and sculpt them into desired shapes. BAR domain proteins are among the central membrane-sculpting proteins in all eukaryote cells. Studies by Pekka Lappalainen laboratory at Institute of Biotechnology, University of...

2013-06-25 13:15:33

Glutamate-like receptor in Arabidopsis does not detect glutamate Plants possess receptors which are similar to the glutamate receptors in the brain of humans and animals. Biochemists at the Ruhr-Universität Bochum (RUB) with colleagues from the University of Würzburg and the Agricultural University of China in Beijing have discovered that these receptors do not, however, recognize the amino acid glutamate, but many other different amino acids. The team reports in the journal "Science...

Nanosponges Soak Up Toxins Released By Venom And Bacterial Infections
2013-04-15 10:52:43

University of California - San Diego [ Watch The Video ] Engineers at the University of California, San Diego have invented a "nanosponge" capable of safely removing a broad class of dangerous toxins from the bloodstream — including toxins produced by MRSA, E. coli, poisonous snakes and bees. These nanosponges, which thus far have been studied in mice, can neutralize "pore-forming toxins," which destroy cells by poking holes in their cell membranes. Unlike other anti-toxin...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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