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Latest Protein folding Stories

2012-06-12 14:32:13

Rice, UCSD scientists study genomes to reveal contacts, refine methods for protein-folding prediction José Onuchic has become an expert at connecting the dots, but finding connections merely implied by the dots “¦ well, that´s quite a trick. The Rice University biophysicist and his team have created a tool to do just that for proteins and, in the process, have advanced the art of predicting their form and function. In this case, the dots are amino acid...

Tiny Living Machines Self-assemble
2012-06-11 07:44:26

Insight may help the development of methods to treat diseases at the nanoscale Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a study by University of Montreal researchers that was published in Nature Structural and Molecular Biology today. The scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and...

Possible Way To Prevent Brain Cell Death Discovered
2012-05-07 03:29:28

In a new study, a team of UK researchers have reportedly found a way to prevent brain cell death in mice -- a discovery which could ultimately lead to improved treatments for Alzheimer's, Parkinson's, and other neurodegenerative ailments in humans. According to BBC News Health and Science Reporter James Gallagher, scientists at the University of Leicester studied prion disease, which affects mice in much the same way as Alzheimer's, Parkinson's, Huntington's and Creutzfeld-Jacob Disease...

2012-04-25 12:03:57

Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal. Picking an ambitious design target with challenging features, the researchers´ success bodes well for the technique´s use in better understanding proteins´ makeup...

2012-04-25 00:01:17

An international team of researchers has reported a new understanding of a little-known process that happens in virtually every cell of our bodies. Protein folding is the process by which not-yet folded chains of amino acids assume their specific shapes, hence taking on their specific functions. These functions vary widely: In the human body, proteins fold to become muscles, hormones, enzymes, and various other components. "This protein folding process is still a big mystery," said UC...

2012-04-11 14:44:45

Computer modeling supports theory that many dementias spread like prion diseases A new technique for analyzing brain images offers the possibility of using magnetic resonance imaging (MRI) to predict the rate of progression and physical path of many degenerative brain diseases, report scientists at the San Francisco VA Medical Center and the University of California, San Francisco. The technique, developed by SFVAMC scientists in collaboration with a team led by Bruce Miller, MD,...

2012-03-14 21:30:27

New method of monitoring protein molecules using gold nanoparticles Scientists at Johannes Gutenberg University Mainz (JGU) in Germany have developed a new method of observing individual proteins. Detailed knowledge of the dynamics of proteins is necessary in order to understand the related biological processes that occur on the molecular level. To date, this information has been obtained by means of labeling proteins with fluorescent substances, but unfortunately this changes the proteins...

2012-03-09 01:43:43

Max Planck scientists identify key player of protein folding Proteins are the molecular building blocks and machinery of cells and involved in practically all biological processes. To fulfil their tasks, they need to be folded into a complicated three-dimensional structure. Scientists from the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, have now analysed one of the key players of this folding process: the molecular chaperone DnaK. “The...

2012-02-10 00:09:01

Findings Suggest New View of “Mad Cow” and Other Neurodegenerative Diseases Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in “mad cow” disease, but is at least 10 times more lethal than larger prion species. This toxic single molecule or “monomer” challenges the prevailing concept that neuronal damage is linked to the toxicity of prion protein...

2012-01-23 22:29:14

Defective proteins that are not disposed of by the body can cause diseases such as Alzheimer's or Parkinson's. Scientists at the Max Planck Institute (MPI) of Biochemistry recently succeeded in revealing the structure of the cellular protein degradation machinery (26S proteasome) by combining different methods of structural biology. The results of collaboration with colleagues from the University of California, San Francisco and the Swiss Federal Institute of Technology Zurich (ETH...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.