Latest Protein folding Stories
Proteins are the molecular building blocks and machinery of cells and involved in practically all biological processes.
Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in “mad cow” disease, but is at least 10 times more lethal than larger prion species.
Defective proteins that are not disposed of by the body can cause diseases such as Alzheimer's or Parkinson's.
Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic lateral sclerosis (ALS), cancer, cystic fibrosis and type 2 diabetes.
The binding of proteins to various substrates in a biological system is a basic but essential process to maintain the function of living things.
A protein's function depends on both the chains of molecules it is made of and the way those chains are folded.
A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder known as Fabry disease.
Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell.
An Oak Ridge National Laboratory invention able to quickly predict three-dimensional structure of protein could have huge implications for drug discovery and human health.
In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with "misfolded" proteins.