Quantcast

Latest Protein kinases Stories

2011-04-02 00:00:03

Crown Bioscience, Inc. announces their partnership with Allostem Therapeutics providing discovery and pre-clinical translational oncology services for Allostem's MEK inhibitor program. CIP-137401 is the clinical candidate from a novel MEK inhibitor scaffold with Best-In-Class potential. Santa Clara, CA (PRWEB) April 1, 2011 Crown Bioscience, Inc. announces their partnership with Allostem Therapeutics (Farmington, CT) providing discovery and pre-clinical Cancer Biology services for...

2011-03-15 07:30:00

QUÓ°BEC CITY, March 15 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZ) (the "Company") today announced that its Senior Director, Head of Preclinical Development, Michael Teifel, Ph.D., will present preclinical results for PI3K/Erk inhibitors AEZS-129, AEZS-131, and AEZS-132, which support further evaluation as potential anticancer compounds. This oral presentation will be made during the Informa Life Sciences Protein Kinases...

2011-03-01 08:00:00

JAMAICA PLAIN, Mass., March 1, 2011 /PRNewswire/ -- Paloma Pharmaceuticals, Inc. announced today updates on its age-related macular degeneration Phase I trials and oncology program. Palomid 529 (P529), Paloma Pharmaceuticals first-in-class allosteric dual TORC1/TORC2 dissociative inhibitor targeting the PI3K/Akt/mTOR pathway, has successfully completed the Company's first three cohorts of its Phase I intravitreal administration trial in patients with age-related macular degeneration...

2011-02-28 07:00:00

SINGAPORE, Feb. 28, 2011 /PRNewswire/ -- S*BIO Pte Ltd today announced that its novel dual mTOR/PI3 Kinase inhibitor SB2343 demonstrated excellent pharmacokinetic/pharmacodynamic (PK/PD) properties leading to significant anti-tumor efficacy in rapamycin-sensitive and resistant xenograft models. In vivo and in vitro data on SB2343 were presented at American Association of Cancer Research (AACR) Special Conference on Targeting PI3K/mTOR Signaling in Cancer held in San Francisco. SB2343 is...

2011-02-23 06:00:00

Prediction of over 30 million human kinase-substrate interactions now available at PhosphoNET website VANCOUVER, BC, Feb. 23 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced another major expansion in its PhosphoNET KnowledgeBase (www.phosphonet.ca) for the study of cell communication systems. This open access, online resource for the scientific community now features data on over 93,000 experimentally-confirmed human...

2010-12-01 22:49:16

University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein results in an abnormal number of chromosomes and a high rate of cell death. The finding demonstrates that stem cells are metabolically different from other blood-forming cells, which can divide without the protein, Lkb1. This metabolic difference could someday be used to better control the behavior...

2010-10-28 22:16:04

The discovery that a protein called Rictor plays a key role in destroying a close cousin of the AKT oncogene could provide scientists with a new molecular target for treating certain cancers, including breast cancer. Described in the September 2010 issue of the journal Molecular Cell, the study was led by scientists at Beth Israel Deaconess Medical Center (BIDMC). The oncogenic cousin, known as SGK1, resembles the widely known AKT oncogene in structure, according to the study's senior author...

2010-07-15 02:43:36

Scientists are making progress towards a better understanding of the neuropathology associated with debilitating psychiatric illnesses like bipolar disorder and schizophrenia. New research, published by Cell Press in the July 15 issue of the journal Neuron, reveals mechanisms that connect a known psychiatric risk gene to disruptions in brain cell proliferation and migration during development. A research group led by Dr. Li-Huei Tsai from the Massachusetts Institute of Technology had recently...

2010-06-29 02:37:53

Cancer occurs when human cells move and multiply inappropriately. Within cells, a process called phosphorylation serves as an on/off switch for a number of cellular processes that can be involved in cancer, including metabolism, transcription, configuration, movement, cell death and differentiation. This process is controlled by a group of enzymes called protein kinases that "“ working together and separately "“ modify the structure of proteins, changing them and allowing them to...

2010-06-09 06:00:00

Prediction of over 4.6 million human kinase-substrate interactions available in PhosphoNET website VANCOUVER, June 9 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular communications research, announced major advancements in its PhosphoNET KnowledgeBase (www.phosphonet.ca) for the study of cell signalling systems. This free resource to the scientific community now features data on more than 92,000 human phosphorylation sites, including their occurrence in over 20...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
Related