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Latest Protein kinases Stories

2009-10-16 08:59:00

NEW YORK, Oct. 16 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Reportlinker Adds Competitor Analysis: PI3K-AKT-mTOR Inhibitors http://www.reportlinker.com/p0154665/Reportlinker-Adds-Competitor-Analysis-PI3K-AKT-mTOR-Inhibitors.html Product description The present Competitive Intelligence Report about PI3K-AKT-mTOR Inhibitors provides a competitor evaluation in the field of novel molecular entities inhibiting members of...

2009-08-27 16:58:37

 The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science."The mechanism that we discovered activates Akt and also contributes to hyperactivation of a mutant form of Akt found in breast, colon and other cancers," said senior author Hui-Kuan Lin, Ph.D., assistant professor in M....

2009-08-11 14:29:15

A new study by researchers at Wake Forest University School of Medicine may reveal how long-lasting memories form in the brain.The researchers hope that the findings, now available online and scheduled to appear in an upcoming issue of Neuroscience, may one day help scientists develop treatments to prevent and treat conditions such as post-traumatic stress disorder."Although many things are known about memories that form from repeat experiences, not much is known with regard to how some...

2009-06-18 02:06:00

LAUSANNE, Switzerland and TAMPA, Florida, June 18 /PRNewswire/ -- Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, and Moffitt Cancer Center (Moffitt), a non-profit Florida corporation, announce the signature of an exclusive license agreement for the development and commercialization of Debio 0928, a small molecule in early preclinical development that inhibits...

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2009-06-15 16:30:00

Tumor metabolism discovery opens new detection and treatment possibilities for rare form of colon cancerPeople who suffer from Peutz-Jeghers syndrome, a rare inherited cancer syndrome, develop gastrointestinal polyps and are predisposed to colon cancer and other tumor types. Carefully tracing the cellular chain-of-command that links nutrient intake to cell growth (and which is interrupted in Peutz-Jeghers syndrome), allowed researchers at the Salk Institute for Biological Studies to exploit...

2009-06-10 10:13:20

Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. Recent research has found that the expression of hepatic TRB3 increased in a rat model of diabetes. TRB3 could block the insulin signaling pathway through inhibiting Akt activation, which contributes to insulin resistance. A research article to be published on May 21, 2009 in the World Journal of Gastroenterology addresses this question. This research, lead by Dr. Yu-Gang Wang and...

2009-05-19 06:00:00

INDIANAPOLIS, May 19 /PRNewswire/ -- Semafore Pharmaceuticals, Inc., a privately held cancer drug discovery and development company, today announced that it will be reporting Phase I clinical data on its vascular targeted pan-PI3K/mTORC1/2 inhibitor, SF1126, during the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting, being held in Orlando, Florida, May 29 through June 2, 2009. The presentation for Semafore's vascular targeted pan-PI3K/mTOR inhibitor is scheduled as follows:...

2009-05-18 15:05:00

SEATTLE, May 18 /PRNewswire-FirstCall/ - Oncothyreon Inc. (Nasdaq: ONTY) (TSX: ONY) today announced the presentation of data demonstrating the effectiveness of Oncothyreon's PX-866 in a preclinical model of pulmonary fibrosis. The data were presented earlier today by William D. Hardie, M.D., Associate Professor, Pulmonary Medicine, Children's Hospital Medical Center, Cincinnati, Ohio, at the American Thoracic Society International Conference in San Diego, California. PX-866 is a small...

2009-05-13 07:30:00

ST. LOUIS, May 13 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) today introduced Precisio(TM) Kinases (www.sigma.com/precisiokinases), a new collection of high quality active kinases that is expected to enable scientists to achieve greater insight into protein phosphorylation and cell signaling. Optimized for high-throughput kinase screening and profiling, Precisio Kinases allow for the characterization of cellular processes and may contribute to new therapeutic strategies for...

2009-04-10 07:59:43

Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell Press in the April 10th issue of the journal Molecular Cell, describes the regulation of a previously uncharacterized protein and demonstrates that it plays an important role in cancer cell invasion.Many cancers, including melanoma, are associated with mutations in the gene...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'