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Latest Protein methods Stories

2009-06-01 15:04:13

 High-throughput whole-genome analysis is becoming a standard laboratory approach for investigating cellular processes. Next-generation sequencing is replacing microarrays as the technique of choice for genome-scale analysis, because it offers advantages in both sensitivity and scale. The June issue of Cold Spring Harbor Protocols (www.cshprotocols.org/TOCs/toc6_09.dtl) features "Native Chromatin Preparation and Illumina/Solexa Library Construction" from Keji Zhao and colleagues at the...

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2009-05-21 08:03:55

Scripps scientists find unexpected role for proteins: antioxidants Researchers at Scripps Institution of Oceanography at UC San Diego and the Salk Institute for Biological Studies have discovered a family of green fluorescent proteins (GFPs) in a primitive sea animal, along with new clues about the role of the proteins that has nothing to do with their famous glow. GFPs recently gained international attention with the awarding of the 2008 Nobel Prize in Chemistry, shared by UC San Diego's...

2009-05-05 12:00:48

 Many proteins do not function by themselves as stand-alone units. Instead, multiple proteins associate to form larger structures called protein complexes. The May issue of Cold Spring Harbor Protocols (www.cshprotocols.org/TOCs/toc5_09.dtl) features a set of methods that can be used to analyze protein complexes. An additional featured article details the generation of viral vectors for gene transfer."Systematic Monitoring of Protein Complex Composition and Abundance by Blue-Native...

2009-03-26 12:32:00

BURLINGTON, Vt. and SEATTLE, March 26 /PRNewswire/ -- BioMosaics Inc., a cancer biomarker development company, announced today that its monoclonal antibody product (clone 1G12) for detection of Glypican-3 (GPC3) has been validated for use as an immunohistochemical test for diagnosis of Hepatocellular Carcinoma (HCC) by PhenoPath Laboratories. PhenoPath Laboratories is a state-of-the-art reference pathology laboratory providing diagnostic immunohistochemistry (IHC), in situ hybridization...

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2008-11-19 14:55:41

A study published in the scientific journal PLoS ONE highlights how the exploration of the ocean depths can benefit humankind. This is the story of a voyage of discovery, starting with marine animals that glow, the identification of the molecules responsible and their application as marker in living cells. Many marine organisms such as sea anemones and corals produce fluorescent proteins, which come in a variety of dazzling hues. Fluorescent proteins have revolutionized biomedical research by...

2008-11-05 09:00:22

Roche NimbleGen has expanded its growing line of tools for analyzing the epigenome and genome-wide transcriptional regulation mechanisms by launching HD2 (2.1 million probes) arrays and services for chromatin immunoprecipitation (ChIP-chip). NimbleGen ChIP-chip HD2 arrays now provide more than a 5-fold increase in probe density per array, which allows for increasing the coverage of key biological features, such as promoters and CpG islands, and decreasing the number of arrays needed to...

2008-10-09 21:00:19

Osamu Shimomura of Japan and Americans Martin Chalfie and Roger Tsien were honoured for their work on green fluorescent protein, or GFP.Researchers worldwide now use GFP to track such processes as the development of brain cells, the growth of tumours and the spread of cancer cells.It has let them study nerve cell damage from Alzheimer's disease and see how insulin-producing beta cells arise in the pancreas of a growing embryo, for example.The academy compared the impact on science to the...

2008-10-09 09:00:15

By MALCOLM RITTER By Malcolm Ritter The Associated Press NEW YORK Three U.S.-based scientists won a Nobel Prize on Wednesday for turning a glowing green protein from jellyfish into a revolutionary way to watch the tiniest details of life within cells and living creatures. Osamu Shimomura, a Japanese citizen who works in the United States, and Americans Martin Chalfie and Roger Tsien shared the chemistry prize for discovering and developing green fluorescent protein, or GFP. When...

2008-10-09 06:00:18

A TRICK three scientists learned from jellyfish has won them the Nobel Prize for chemistry. Americans Martin Chalfie and Roger Tsien and Osamu Shimomura, from Japan, were honoured for their discovery of the green fluorescent protein that allows the creatures to glow. The "glowing markers" are now to tag and track biological systems, for example how cancer cells spread. (c) 2008 Daily Record; Glasgow (UK). Provided by ProQuest LLC. All rights Reserved.

2008-10-09 06:00:18

By Kenneth Chang One Japanese and two American scientists have received the 2008 Nobel Prize in Chemistry for taking the ability of some jellyfish to glow green and transforming it into a ubiquitous tool of molecular biology to watch the dance of living cells and the proteins within them. The new laureates are Osamu Shimomura, a Japanese-born emeritus professor at the Marine Biological Laboratory in Woods Hole, Massachusetts, and Boston University Medical School; Martin Chalfie, a...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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