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Latest Protein structure Stories

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2010-03-01 07:28:03

A new technique to study protein dynamics in living cells has been created by a team of University of Illinois scientists, and evidence yielded from the new method indicates that an in vivo environment strongly modulates a protein's stability and folding rate, according to research accepted for publication in the journal Nature Methods and posted on the journal's Web site Feb. 28. Martin Gruebele, the James R. Eiszner Professor of Chemistry at Illinois and corresponding author of the paper,...

2010-02-13 09:20:34

The National Center for Macromolecular Imaging at Baylor College of Medicine has received a five-year, $9.5 million award from the National Center for Research Resources, maintaining a record of more than 24 years of support to advance the development of research technology in the field of electron cryo-microscopy. NCRR, part of the National Institutes of Health, supports scientists and clinical researchers to advance critical technologies in structural biology, genomics, proteomics, imaging...

2010-01-19 12:49:08

Single-molecule, real-time measurements of a key biological process Biophysicists at TUM, the Technische Universitaet Muenchen, have published the results of single-molecule experiments that bring a higher-resolution tool to the study of protein folding. How proteins arrive at the three-dimensional shapes that determine their essential functions "“ or cause grave diseases when folding goes wrong "“ is considered one of the most important and least understood questions in the...

c1c581a12e25f045322cefd19d453676
2009-12-02 15:48:41

For the first time, experimental evidence shows that hidden protein structures are essential for catalysis An important Brandeis study appearing in the December 3 issue of Nature raises the curtain on the hidden lives of proteins at the atomic level. The study reports that for the first time, researchers used x-ray crystallography and nuclear magnetic resonance (NMR) techniques to directly visualize protein structures essential for catalysis at the rare high-energy state. The study also...

2009-10-02 08:54:45

Discovery could lead to treatments for learning and memory deficits, particularly Noonan's syndrome As most good students realize, repeated studying produces good memory. Those who study a lot realize, further, that what they learn tends to be preserved longer in memory if they space out learning sessions between rest intervals. Neuroscientists at Cold Spring Harbor Laboratory (CSHL) have now discovered how this so-called "spacing effect" is controlled in the brain at the level of individual...

2009-09-23 07:50:49

The National Institute of Standards and Technology (NIST) has issued a new ruler, and even for an organization that routinely deals in superlatives, it sets some records. Designed to be the most accurate commercially available "meter stick" for the nano world, the new measuring tool"”a calibration standard for X-ray diffraction"”boasts uncertainties below a femtometer. That's 0.000 000 000 000 001 meter, or roughly the size of a neutron. The new ruler is in the form of a thin,...

5da61b6983f0e3105e043ff27911b8151
2009-09-17 09:45:31

UAB researchers discover that the separation of 2 or more proteins due to genetic mutations causes them to malfunction Researchers at the Department of Biochemistry and Molecular Biology of Universitat Autònoma de Barcelona (UAB) have revealed the process by which proteins with a tendency to cause conformational diseases such as amyotrophic lateral sclerosis, familial amyloidotic polyneuropathy, familial amyloidotic cardiomyopathy, etc. finally end up causing them....

2009-09-13 12:41:26

Reveals shape-shifting atomic interactions; suggests mechanism and possible drug targets How much difference can a tenth of a nanometer make? When it comes to figuring out how proteins work, an improvement in resolution of that miniscule amount can mean the difference between seeing where atoms are and understanding how they interact. Case in point: New, improved-resolution views of a zinc transporter protein deciphered at the U.S. Department of Energy's Brookhaven National Laboratory provide...

2f4b47ef41c44a3d4c3389ada0d986e71
2009-08-21 08:35:00

What are the causes of illness? How can the effect of medication be improved? Molecular biologists can now gain new insights by the virtual simulations generated with a new type of software.If it's a question of the efficacy of vaccines or the aggressiveness of toxins, researchers must be able to simulate and analyze the molecules involved in three dimensions. What do they look like? What is the three-dimensional structure of a protein? How can this structure be used to predict which...

2009-08-20 13:48:47

U.S. scientists say they have discovered protein-shape changes affect drug binding. Computational biologists at the University of Pittsburgh School of Medicine have shown proteins have an intrinsic ability to change shape, and that allows small molecules that are attracted to a given protein to select the structure that permits the best binding. The researchers say that premise could help in drug discovery and in designing compounds that will have the most impact on protein function to better...


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bellycheer
  • Good cheer; viands.
  • To revel; to feast.
The word 'bellycheer' may come from 'belle cheer', "good cheer".
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