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Latest Protein structure Stories

2012-06-11 21:50:23

Researchers work to untangle knots, slipknots in species separated by a billion years of evolution Strings of all kinds, when jostled, wind up in knots. It turns out that happens even when the strings are long strands of molecules that make up proteins. A new study by scientists at Rice University and elsewhere examines structures of proteins that not only twist and turn themselves into knots, but also form slipknots that, if anybody could actually see them, might look like shoelaces...

Tiny Living Machines Self-assemble
2012-06-11 07:44:26

Insight may help the development of methods to treat diseases at the nanoscale Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a study by University of Montreal researchers that was published in Nature Structural and Molecular Biology today. The scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and...

2012-06-05 10:01:37

A new study suggests that protein knots, a structure whose formation remains a mystery, may have specific functional advantages that depend on the nature of the protein's architecture. "The presence of a knotted or slipknotted structure in a protein is relatively rare but really is very interesting," said Kenneth Millett, a professor of mathematics at UC Santa Barbara and a co-author of the paper, "Conservation of complex knotting and slipknotting patterns in proteins," published in the...

2012-06-04 04:22:24

(Ivanhoe Newswire) -- The structure of biomolecules is of great interest for medicine and biology because their shape often determines their function. The use of new tools called free-electron lasers (FELs) allows scientists to obtain high-resolution structural insight into macromolecules. "The exceptionally intense X-ray pulses possible with FELs open the door for analyzing completely new classes of biomolecules like proteins from the cell membrane, that are hard or nearly impossible to...

2012-05-25 10:15:43

There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments. The findings, just published in the journal Science, could lead to new understanding of the molecules that drive processes in biology, medical diagnostics, nanotechnology and other fields. Like...

2012-04-25 12:03:57

Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal. Picking an ambitious design target with challenging features, the researchers´ success bodes well for the technique´s use in better understanding proteins´ makeup...

2012-04-25 00:01:17

An international team of researchers has reported a new understanding of a little-known process that happens in virtually every cell of our bodies. Protein folding is the process by which not-yet folded chains of amino acids assume their specific shapes, hence taking on their specific functions. These functions vary widely: In the human body, proteins fold to become muscles, hormones, enzymes, and various other components. "This protein folding process is still a big mystery," said UC...

2012-03-22 13:41:09

UCLA researchers are now able to peer deep within the world's tiniest structures to create three-dimensional images of individual atoms and their positions. Their research, published March 22 in the journal Nature, presents a new method for directly measuring the atomic structure of nanomaterials. "This is the first experiment where we can directly see local structures in three dimensions at atomic-scale resolution – that's never been done before," said Jianwei (John) Miao, a...

2012-03-19 16:58:18

Study outlines new method to test a tumor's resistance to an experimental therapy and pinpoint the genetic culprit before testing the drug in patients–providing a new path toward personalized medicine Drug resistance is a serious problem for cancer patients–over time, a therapy that was once providing some benefit simply stops working. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) recently discovered how cancer cells develop resistance to a drug...

2012-03-19 16:05:01

A new method to reveal the structure of proteins could help researchers understand biological molecules — both those involved in causing disease and those performing critical functions in healthy cells.   For roughly a decade, a technique called solid state nuclear magnetic resonance (NMR) spectroscopy has allowed researchers to detect the arrangements of atoms in proteins that defy study by traditional laboratory tools such as X-ray crystallography. But translating solid state...


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