Quantcast

Latest Proteins Stories

2013-11-26 14:00:16

Rice U. researchers find misfolded proteins are capable of forming tree-like aggregates A method by Rice University researchers to model the way proteins fold – and sometimes misfold – has revealed branching behavior that may have implications for Alzheimer’s and other aggregation diseases. Results from the research will appear online this week in the Proceedings of the National Academy of Sciences. In an earlier study of the muscle protein titin, Rice chemist Peter Wolynes...

2013-11-22 23:20:45

Histone Methyltransferases: Global Markets for Research Tools, Diagnostics and Drug Discovery, increased R&D spending in the development of epigenetic tools and assays for Histone Methyltransferases (HMT) research, HMTs use as biomarkers and targets for diagnostics development and the drug discovery sector will drive tremendous growth in this market for the foreseeable future. BCC Research projects the market to grow to $275 million by 2018, and register a five-year compound annual...

Two Human Proteins Found To Affect How 'Jumping Gene' Gets Around
2013-11-21 13:55:24

Johns Hopkins Medicine Using a new method to catch elusive "jumping genes" in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. The discovery, described in the Nov. 21 issue of Cell, breaks new ground, they say, in understanding the arms race between a jumping gene driven to colonize new areas of the human genome and cells working to limit the risk posed by such volatile bits of DNA. Jumping genes, more...

2013-11-21 13:11:59

Findings have implications for oncology, diabetes drug development Drugs that inhibit the activity of enzymes called histone deacetylases (HDACs) are being widely developed for treating cancer and other diseases, with two already on the market. Researchers at the Perelman School of Medicine, University of Pennsylvania, show that a major HDAC still functions in mice even when its enzyme activity is abolished, suggesting that the beneficial effects of HDAC inhibitors may not actually be...

2013-11-19 12:22:00

Drugs known as PDE3 inhibitors save many lives by helping failing hearts do a better job of pumping blood. But those same medications come with a sometimes deadly cost when taken for long periods: an increased risk for sudden cardiac death. The drugs work by inhibiting PDE3A, an enzyme that regulates how the heart pumps blood. When PDE3A is inhibited, the heart contracts more forcefully, pumping more blood. Developing a medication that has the benefits of current drugs but doesn't...

Researchers Exploit Power Of Evolution To Create Designer Proteins
2013-11-15 10:18:45

University of Leicester An international team of researchers led by the University of Leicester has "harnessed the power of evolution" to create a new drug for possible use against heart disease, inflammation and other illnesses. Researchers in the Department of Cardiovascular Sciences and Department of Biochemistry at the University of Leicester, together with colleagues in Cambridge, the USA and Italy, have employed a new technique to create protein-based drugs. According to...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.