Latest Proteome Stories

Max-Planck-Gesellschaft The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system, the scientists of the Max Planck Institute of Biochemistry in Martinsried near Munich and their collaboration partners at the University of California in San Francisco have shown that the genome of this...

Ribosome-mapping technique may provide insights into other viral proteomes as well New findings reveal the surprisingly complex protein-coding capacity of the human cytomegalovirus, or HCMV, and provide the first steps toward understanding how the virus manipulates human cells during infection. The genome of the HCMV was first sequenced over 20 years ago, but researchers have now investigated the proteome—the complete set of expressed proteins—of this common pathogen as well. HCMV...

Scientists are announcing the roadmap, policies and procedures for an ambitious international project that aims to compile a landmark sequel to "The Book of Life." The follow-up to the Human Genome Project, which decoded all of the genes that make up humans, involves identifying and profiling all of the proteins produced by the thousands of genes bundled together in all of the human chromosomes. Called the Chromosome-Centric Human Proteome Project (C-HPP), it is the topic of an article in...

SAN DIEGO, Feb. 7, 2012 /PRNewswire/ -- Applied Proteomics Inc. (API), powering the proteome to transform diagnostics, announced today the appointment of veteran diagnostic developer, Peter Klemm, Ph.D., as chief executive officer. API also announced the move of the corporate headquarters to San Diego. Prior to the move, API secured a $22.5 million Series B financing from Domain Associates, Vulcan Capital and returning angel investors. In conjunction with the financing, James C....

Crops that can cope with sudden fluctuations in the weather could be developed, thanks to fresh discoveries about the survival mechanisms of plants Crops that can cope with sudden fluctuations in the weather could be developed, thanks to fresh discoveries about the survival mechanisms of plants. Scientists studying how tiny algae renew old or damaged cell proteins say their findings could be useful in developing crops suited to climates in which weather changes quickly. Researchers...

BERLIN and BURLINGTON, Mass., Dec. 6, 2011 /PRNewswire/ -- caprotec bioanalytics GmbH announced today that it has initiated a research collaboration with Bayer CropScience. Under the collaborative research agreement, caprotec will use its proprietary CCMS (Capture Compound Mass Spectrometry) technology to profile the interactions of one of Bayer CropScience's undisclosed new active ingredients in the relevant biological system. "We are very excited about the...

Scientists have reported for the first time ever the genomic sequence of the iconic Monarch Butterfly in the journal Cell. The Monarch butterfly is mostly famous for its migration of 2,000 miles from North America to central Mexico every fall. The new genome is the first for any butterfly, and is also the first complete genome of any long-distance migrant. "With this genome sequence in hand, we now have an overwhelming number of opportunities to understand the genetic and molecular...

New top-down strategy of identifying proteins could lead to early detection of disease The human genome has been mapped. Now, it's on to proteins, a much more daunting task. There are 20,300 genes, but there are millions of distinct protein molecules in our bodies. Many of these hold keys to understanding disease and targeting treatment. A team led by Northwestern University chemical biologist Neil Kelleher has developed a new "top-down" method that can separate and identify thousands...

In an advance toward a much-needed early diagnostic test for Alzheimer's disease (AD), scientists have discovered that older women destined to develop AD have high blood levels of a protein linked to pregnancy years before showing symptoms. Their report appears in ACS' Journal of Proteome Research. Theo Luider and colleagues explain that more than 26 million people worldwide already have AD, and the numbers are rising with the graying of the population. Doctors can prescribe any of several...

Changes in cell signaling proteins are induced at lower doses in female rats compared to males VANCOUVER, Aug. 4, 2011 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced today the publication of the results from a major study undertaken in collaboration with the A. W. Spears Research Center, Lorillard Tobacco Company to uncover cigarette smoke protein biomarkers. The findings appear in the Journal of Proteome Research...