Latest proteomics Stories

2012-06-12 14:32:13

Rice, UCSD scientists study genomes to reveal contacts, refine methods for protein-folding prediction José Onuchic has become an expert at connecting the dots, but finding connections merely implied by the dots “¦ well, that´s quite a trick. The Rice University biophysicist and his team have created a tool to do just that for proteins and, in the process, have advanced the art of predicting their form and function. In this case, the dots are amino acid...

Tiny Living Machines Self-assemble
2012-06-11 07:44:26

Insight may help the development of methods to treat diseases at the nanoscale Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a study by University of Montreal researchers that was published in Nature Structural and Molecular Biology today. The scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and...

2012-06-08 09:29:35

Prenatal screening for Down syndrome (DS) is still in need of improvement. Perinatal medicine experts have worked hard to find new biomarkers for screening of DS. Dr. Shi he Shao and his co-investigators, from Jiangsu University and Changzhou Woman and Children Health Hospital, report in the May 2012 issue of Experimental Biology and Medicine that they have successfully identified twenty-nine differentially expressed proteins in maternal serum from pregnancies carrying DS fetuses with...

2012-06-05 10:01:37

A new study suggests that protein knots, a structure whose formation remains a mystery, may have specific functional advantages that depend on the nature of the protein's architecture. "The presence of a knotted or slipknotted structure in a protein is relatively rare but really is very interesting," said Kenneth Millett, a professor of mathematics at UC Santa Barbara and a co-author of the paper, "Conservation of complex knotting and slipknotting patterns in proteins," published in the...

2012-06-01 09:27:49

New study creates cells that act like circuits, a step toward developing cellular computers Johns Hopkins scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat, published in the May issue of Nature Chemical Biology, could eventually help researchers create computers that use cells as tiny circuits. Study leader Takanari Inoue, Ph.D., an assistant professor in the Department of Cell Biology and...

2012-05-30 10:56:51

Salk scientists develop new technique for solving the structure of most popular targets for half of all drugs, potentially aiding discovery of new therapeutics A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods. The technique, developed by scientists at the Salk...

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