Latest Proteopathy Stories
A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.
Neuron have discovered an abnormal protein that first forms as a result of genetic abnormalities and later builds up in the brains of many patients with either disease.
Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles.
Amyloid fibers in the brain are a hallmark of many neurodegenerative diseases, including Parkinson's disease, for which there are no effective treatments.
An international team of researchers have developed a new method for measurement of aggregated beta-amyloid – a protein complex believed to cause major nerve cell damage and dysfunction in Alzheimer's disease.
A protein associated with Alzheimerâ€™s disease clogs several motors of the cell transport machinery critical for normal cell division, leading to defective neurons that may contribute to the memory-robbing disease.
Medical therapies may be developed to recover healthy proteins that are important to prevent diseases such as Alzheimer's disease and diabetes ANN ARBOR, Mich., April 27, 2011 /PRNewswire-USNewswire/ -- A computer analysis by two University of Michigan researchers shows promise for helping develop therapies for some major diseases by rescuing proteins that have stopped performing normally.
Pathological protein deposits linked to Alzheimer's disease and cerebral amyloid angiopathy can be triggered not only by the administration of pathogenic misfolded protein fragments directly into the brain but also by peripheral administration outside the brain.
The dramatically new approach to protein misfolding could lead to new therapies for a number of diseases.
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