Latest Prothrombin time Stories
Kcentra(TM) Is the First FDA-Approved 4-Factor Prothrombin Complex Concentrate for Warfarin Reversal in the U.S. KING OF PRUSSIA, Pa., April 30, 2013 /PRNewswire/ -- CSL Behring announced today that the U.S. Food and Drug Administration (FDA) approved Kcentra(TM) (Prothrombin Complex Concentrate [Human]), the first non-activated 4-factor prothrombin complex concentrate (PCC) for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist (e.g.,...
LOS ANGELES, Nov. 7, 2012 /PRNewswire/ -- Twelve-month data from the Global Anticoagulant Registry in the FIELD (GARFIELD) show that poor management of stroke prevention therapy is widespread in everyday clinical practice, which may lead to elevated rates of mortality, stroke and bleeding among individuals with newly diagnosed with atrial fibrillation (AF). Data from the GARFIELD Registry describes AF management and outcomes in everyday clinical practice, highlighting unmet...
INDIANAPOLIS, Oct. 1, 2012 /PRNewswire/ -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the U.S. Food and Drug Administration (FDA) has granted CLIA-waived status to the CoaguChek® XS Plus system, a point-of-care anticoagulation monitor that offers connectivity and data management tools to help healthcare professionals manage PT/INR (blood clotting time) testing. The waiver means that the monitoring technology may now be used in a broader range of clinical settings,...
The clot-busting medicine, tPA (tissue plasminogen activator), is safe to use in acute stroke patients already on the home blood thinner warfarin, according to researchers from Duke Clinical Research Institute (DCRI). This study helps allay previous concerns that tPA was too dangerous to use in patients on home anticoagulation and would lead to high risk for potentially fatal intracranial bleeding. "To date, we have no randomized trials or large cohort studies to guide us," says Ying Xian,...
(Ivanhoe Newswire) – Researchers from the Duke Clinical Research Institute have ruled the clot-busting drug tPA (tissue plasminogen activator) safe for acute stroke patients on the home blood thinner warfarin. The drug was previously thought to be too dangerous to use in patients on home anticoagulation for fear of a higher risk of fatal intracranial bleeding. "To date, we have no randomized trials or large cohort studies to guide us," Ying Xian, M.D., Ph.D., assistant professor of...
CHICAGO, May 4, 2012 /PRNewswire/ -- Data presented by CSL Behring today at the 2012 Thrombosis and Hemostasis Summit of North America (THSNA) showed that the safety profile of human 4-factor prothrombin complex concentrate (PCC) is consistent with the current standard of treatment in patients receiving vitamin K antagonist therapy (i.e., warfarin) for acute bleeding or prior to emergency surgery. The results are from the first large-scale controlled clinical trials comparing a...
MONTGOMERY, Ala., Feb. 13, 2012 /PRNewswire/ -- Kowa Pharmaceuticals America, Inc. today announced data assessing the effect of LIVALO® (pitavastatin) compared with Crestor® (rosuvastatin) on steady-state pharmacodynamics (PD) of warfarin by measuring international normalized ratio (INR) in healthy adult subjects.(1) The study, published in Current Medical Research & Opinion, showed INR during stable warfarin treatment did not change significantly when LIVALO was...
Elderly people with atrial fibrillation are often treated with anticoagulants to thin the blood, but this medicine is hard to dose and patients have to have their blood tested regularly. Researchers at the Sahlgrenska Academy at the University of Gothenburg and Chalmers University of Technology have now devised a new method that improves the accuracy of risk assessments. Atrial fibrillation, or irregular heartbeat, is a very common heart rhythm disturbance that increases the risk of stroke...
Tokyo, Nov 30, 2011 - (JCN Newswire) - Eisai Co., Ltd. announced today that it will launch Warfarin Granules 0.2%, a new formulation of the company's oral anti-coagulant Warfarin (warfarin potassium), on December 1 in Japan.Warfarin Granules 0.2% received marketing authorization in Japan on July 15 of this year and was subsequently listed on Japan's National Health Insurance (NHI) drug price list on November 28. This new formulation is designed to help patients...
RIDGEFIELD, Conn., Aug. 26, 2011 /PRNewswire/ -- Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) today announced plans to launch RE-ALIGN(TM), a global, Phase II trial evaluating the safety and pharmacokinetics of dabigatran etexilate in 400 patients who have mechanical heart valves.(1) The 12-week study will compare three doses of dabigatran etexilate (150mg bid, 220mg bid and 300mg bid) to warfarin in patients with both aortic valve replacements and mitral valve replacements.(1) A...
