Latest PTEN Stories
A person’s hair color and skin tone is determined by their skin pigment. This pigment is influenced by the melanocortin-1 (MC1R) gene receptor. For the world’s redheads – one to two percent of the population – their coloration is accounted for by a mutation in MC1R.
Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics.
Genetic mutations aren’t the only thing that can keep a protein called PTEN from doing its tumor-suppressing job.
A novel gene variant found in human and animal tissue may be a promising treatment for cancer, including breast and brain cancer, according to scientists from the Icahn School of Medicine at Mount
Researchers from the Masonic Cancer Center, University of Minnesota, and the University’s Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors (MPNST) that allow them to discover new genes and gene pathways driving this type of cancer.
Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumor-suppressing PTEN gene.
Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.
Scientists from the University of Texas Medical Branch at Galveston and the University of Houston found a new way to influence the vital serotonin signaling system. The team linked malfunctions in serotonin signaling to a range of health issues, including everything from depression and addictions, to epilepsy and obesity.
The combined loss of two tumor suppressor genes was shown to be strongly associated with progression of DCIS to invasive breast cancer.
- To say in too many words; to express verbosely.
- To express in too many words: sometimes used reflexively.
- The leading idea or a repeated phrase, as of a song or ballad; the refrain; burden.