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Latest Public Library of Science Stories

2013-07-24 11:24:48

Less than five percent of promising basic science discoveries that claim clinical relevance lead to approved drugs within a decade, partly because of flawed pre-clinical animal research. A number of recent initiatives seek to improve the quality of such studies, and an article published this week in PLOS Medicine identifies key experimental procedures believed to increase clinical generalizability. The authors, led by Jonathan Kimmelman of McGill University in Montréal, did a...

2013-07-24 11:18:04

The main barriers to the access, delivery, and use of interventions that help to prevent malaria in pregnant women are relatively consistent across sub-Saharan African countries and may provide a helpful checklist to identify the factors influencing uptake of these important interventions, according to a study published in this week's PLOS Medicine. The analysis by Jenny Hill and colleagues from the Liverpool School of Tropical Medicine in the UK, the London School of Hygiene &...

2013-07-17 10:19:17

A new study published in the open access journal PLOS Biology suggests that the scientific literature could be compromised by substantial bias in the reporting of animal studies, and may be giving a misleading picture of the chances that potential treatments could work in humans. Testing a new therapeutic intervention (such as a drug or surgical procedure) on human subjects is expensive, risky and ethically complex, so the vast majority are first tested on animals. Unfortunately, cost and...

2013-07-17 10:06:02

Many new developments and initiatives have been introduced to improve the quality and translational value of animal research, and must continue with support from the wider scientific community. These are the conclusions of a new article in PLOS Medicine this week by Carlijn Hooijmans and colleagues from the Radboud University Nijmegen Medical Centre, Netherlands, who summarize these new developments. Focusing on the quality of study conduct, reporting, and replication; systematic reviews...

2013-06-27 11:52:32

Less muscle damage, fatigue in 200-mile Alpine race than in 100-mile race Runners who complete one of the world's most challenging ultra-marathons experience less neuromuscular fatigue, muscle damage and inflammation compared to those who run distances half to one quarter as long, according to the results of research published June 26 in the open access journal PLOS ONE by Jonas Saugy and colleagues from the University of Lausanne, Switzerland. The researchers tested the effects of...

2013-06-13 12:33:32

10-month-old infants show sympathy for victims of aggression Infants as young as ten months old express sympathy for others in distress in non-verbal ways, according to research published June 12 in the open access journal PLOS ONE by Yasuhiro Kanakogi and colleagues from Kyoto University and Toyohashi University of Technology, Japan. Infants at this age are known to assign goals and intentions to geometric figures; hence the researchers used a series of animated sequences to test...

2013-06-12 16:03:16

People in India who walk or cycle to work are less likely to be overweight or obese, according to a study led by Christopher Millett from Imperial College London and the Public Health Foundation of India and colleagues. Their paper reporting the study, published in this week's PLOS Medicine, reveals that cyclists are also less likely to have diabetes or high blood pressure compared to people who take public or private transport to work. These findings are important as they suggest that...

New Short-tailed Whipscorpion Species Inhabit Limestone Caves In Brazil
2013-05-23 11:35:18

Public Library of Science Two new species of cave-dwelling short-tailed whipscorpions have been discovered in northeastern Brazil, and are described in research published May 22 in the open access journal PLOS ONE by Adalberto Santos, from the Federal University of Minas Gerais (Brazil) and colleagues. The reddish-brown short-tailed whipscorpions inhabit cool, humid limestone caves in an otherwise arid region. Both new species, Rowlandius ubajara and Rowlandius potiguara, were found...

Species Recovery Programs May Spread Antibiotic Resistant Genes To Wild Populations
2013-05-23 10:37:49

Public Library of Science Endangered brush-tail rock wallabies raised in captive breeding programs carry antibiotic resistance genes in their gut bacteria and may be able to transmit these genes into wild populations, according to research published May 22 in the open access journal PLOS ONE by Michelle Power and colleagues from Macquarie University in New South Wales, Australia. Brush-tail rock wallabies are currently being raised in species recovery programs and restored to the wild...

Ants Benefit Pitcher Plant Hosts By Hunting Nutrient Stealing Parasites
2013-05-23 10:00:53

[ Watch The Video: Movie of Camponotus Schmitzi ] Public Library of Science An insect-eating pitcher plant teams up with ants to prevent mosquito larvae from stealing its nutrients, according to research published May 22 in the open access journal PLOS ONE by Mathias Scharmann and colleagues from the University of Cambridge and the University Brunei Darussalam. The unusual relationship between insect-eating pitcher plants and ants that live exclusively on them has long puzzled...


Latest Public Library of Science Reference Libraries

PLoS Medicine
2012-05-17 15:12:48

PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...

PLoS Biology
2012-05-02 19:40:12

PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...

PLoS ONE
2012-04-30 14:56:25

PLoS ONE is an open-access peer-reviewed scientific journal published by the Public Library of Science (PLoS). It was established in 2006 as a beta version. In August 2008 it moved from a weekly publication schedule to a daily one, publishing articles as soon as they became ready. In October 2008, it came out of “beta.” In September 2009, PLoS ONE made full online usage of every published article publicly available. The founding managing editor was Chris Surridge. He was succeeded by...

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