Latest Purkinje cell Stories
New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain.
Research at the University of Calgary's Hotchkiss Brain Institute (HBI) has demonstrated the novel expression of an ion channel in Purkinje cells – specialized neurons in the cerebellum, the area of the brain responsible for movement.
Defective mitochondria, the energy-producing powerhouses of the cell, trigger an inherited neurodegenerative disorder that first shows itself in toddlers just as they are beginning to walk.
When Dr. John Fryer and Dr. Huda Zoghbi prescribed mild exercise for mice with a neurodegenerative disorder called spinocerebellar ataxia 1 (SCA1), they did not know what to expect.
Unlike conventional methods, with the so-called optogenetics, the researchers are able to target one cell type.
Hereditary diseases such as epilepsy or various coordination disorders may be caused by changes in nerve cells of the cerebellum, which do not set in until after birth.
The brain makes mistakes and then corrects them, according to a new study.
In the developing brain, countless nerve connections are made which turn out to be inappropriate and as a result must eventually be removed.
A team of researchers, led by scientists at the University of California, San Diego, have identified a key player in the dramatic loss of neurons in mice and fly models, a discovery that could help illuminate the role of mitochondrial dysfunction in human neurodegenerative disorders, such as Parkinson's disease.
The neurodegenerative disease spinocerebellar ataxia type 5 (SCA5) damages nerve cells in two ways.
The cerebellum is a section of the brain that is most in charge of cognitive functions and motor skills. Formation and Orientation The cerebellum can be found at the bottom of the brain behind the pons and below that cerebral cortex under a layer of dura mater. It is considered as a part of the "hindbrain". The cerebellum is anatomically divided into two separate hemispheres, marked by the 'vermis', a small midline zone between the left and right hemispheres. But three lobes can be...
- totally perplexed and mixed up.