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Latest Purkinje cell Stories

2014-07-21 09:52:36

Washington University in St. Louis New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body. Reporting online in Neuron, researchers at Washington University School of Medicine in St. Louis have identified a group of proteins that program a common type of brain nerve cell to connect with another...

2012-03-21 14:04:30

Researchers identify the novel expression of an ion channel in neurons of the brain Research at the University of Calgary's Hotchkiss Brain Institute (HBI) has demonstrated the novel expression of an ion channel in Purkinje cells — specialized neurons in the cerebellum, the area of the brain responsible for movement. Ray W. Turner, PhD, Professor in the Department of Cell Biology & Anatomy and PhD student Jordan Engbers and colleagues published this finding in the January edition...

2011-12-06 23:16:52

Research presented at ASCB annual meeting Defective mitochondria, the energy-producing powerhouses of the cell, trigger an inherited neurodegenerative disorder that first shows itself in toddlers just as they are beginning to walk, Canadian scientists reported at the American Society for Cell Biology Annual Meeting, Dec. 6, in Denver. The disorder, Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS), was first identified in the late 1970s among the descendants of a small...

2011-11-04 22:56:24

When Dr. John Fryer and Dr. Huda Zoghbi prescribed mild exercise for mice with a neurodegenerative disorder called spinocerebellar ataxia 1 (SCA1), they did not know what to expect. Fryer, then a postdoctoral associate in the lab of Zoghbi, the Baylor College of Medicine researcher who co-discovered the gene for the disorder, was disappointed when the exercise did not affect the mice's gait or walking ability. However, he and Zoghbi decided to put them back in their cages and see what...

2011-07-20 14:37:08

Researchers influence activity of nerve cells with laser light Unlike conventional methods, with the so-called optogenetics, the researchers are able to target one cell type. "We are now going to use this method to find out exactly what goes wrong in the nerve cells in movement disorders such as ataxias", said Prof. Dr. Stefan Herlitze (RUB Department for Biology and Biotechnology). The researchers report in the Journal of Biological Chemistry. The Bochum team examined a specific signaling...

2011-03-18 15:12:49

Epilepsy trigger discovered Bochum's neuroscientists report on new treatment possibilities Hereditary diseases such as epilepsy or various coordination disorders may be caused by changes in nerve cells of the cerebellum, which do not set in until after birth. This is reported by Bochum's neuroscientists in the Journal of Neuroscience. The team of Prof. Dr. Stefan Herlitze, the Chair of the Department of Zoology and Neurobiology at RUB, showed that the diseases broke out in mice if, a week...

2011-02-14 08:33:17

(Ivanhoe Newswire) -- The brain makes mistakes and then corrects them, according to a new study. A research group, led by Dr. Peter Scheiffele at the Biozentrum of the University of Basel, was able to document the brain's process of establishing a neuronal network that does not always prove precise or error-free. In the developing brain, countless nerve connections are made, which turn out to be inappropriate, and as a result, must eventually be removed. Using a genetic mouse model, the...

2011-02-09 12:44:45

In the developing brain, countless nerve connections are made which turn out to be inappropriate and as a result must eventually be removed. The process of establishing a neuronal network does not always prove precise or error free. Dr. Peter Scheiffele's research group at the Biozentrum of the University of Basel have been able to document this phenomenon using advanced microscopy techniques in the developing cerebellum, a brain area required for fine movement control. Dr. Scheiffele's group...

2010-06-25 13:22:29

Animal models offer clues to similar neurodegenerative disorders in humans, such as Parkinson's A team of researchers, led by scientists at the University of California, San Diego, have identified a key player in the dramatic loss of neurons in mice and fly models, a discovery that could help illuminate the role of mitochondrial dysfunction in human neurodegenerative disorders, such as Parkinson's disease. Writing in the June 24 issue of Neuron, principal investigator Albert La Spada, MD,...

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2010-04-05 09:40:27

The neurodegenerative disease spinocerebellar ataxia type 5 (SCA5) damages nerve cells in two ways. University of Minnesota researchers now report that the defective protein responsible for the disease cuts the number of synaptic terminals and snarls traffic inside neurons. The study appears in the April 5 issue of the Journal of Cell Biology. SCA5 results from a faulty gene for {beta}-III"“spectrin. The disease targets the cerebellum's Purkinje cells, which control coordination....


Latest Purkinje cell Reference Libraries

Cerebellum
2013-07-29 09:48:00

The cerebellum is a section of the brain that is most in charge of cognitive functions and motor skills. Formation and Orientation The cerebellum can be found at the bottom of the brain behind the pons and below that cerebral cortex under a layer of dura mater. It is considered as a part of the "hindbrain". The cerebellum is anatomically divided into two separate hemispheres, marked by the 'vermis', a small midline zone between the left and right hemispheres. But three lobes can be...

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Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.