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Latest Pyrimethamine Stories

2013-02-13 10:34:36

Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower risk of low birth weight than the current standard 2-dose regimen, according to a review and meta-analysis of previous studies published in the February 13 issue of JAMA. "Intermittent preventive therapy with sulfadoxine-pyrimethamine to control malaria during pregnancy is used in 37...

2012-04-02 20:51:06

Malaria infections among infants can be cut by up to 30 per cent when antimalarial drugs are given intermittently over a 12 month period, a three-year clinical trial in Papua New Guinea has shown. The trial showed the drug regime was effective against both Plasmodium falciparum and Plasmodium vivax malaria, the first time antimalarial drugs have been shown to prevent infections by both species of malaria. The treatment regime, called intermittent preventive treatment (IPT), protected the...

2011-11-15 20:57:35

A study conducted by researchers at the Johns Hopkins Malaria Research Institute and their Zambian colleagues detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes in rural Zambia. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria in the region. However, parasites taken from mosquitoes themselves had very low...

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2009-02-26 07:10:00

A disease once thought to be somewhat under control with the use of prescription drugs is emerging at the Thai-Cambodian border as drug resistant. The World Health Organization said Wednesday the new strain of malaria could "seriously undermine" efforts to bring the disease under control. "Surveillance systems and research studies... are providing new evidence that parasites resistant to artemisinin have emerged along the border between Cambodia and Thailand where workers walk for miles...

2005-10-18 22:14:15

A drug combination used to prevent pneumonia and opportunistic bacterial infection in persons with HIV/AIDS has unexpectedly been found to be highly effective at preventing malaria, according to a study published in the November 15 issue of The Journal of Infectious Diseases, now available online. The combination, trimethoprim-sulfamethoxazole (TS), is known to reduce morbidity and mortality from certain opportunistic infections in HIV-infected individuals, and is widely recommended for...


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ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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