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Latest Quinolines Stories

2014-07-17 16:26:09

NEW YORK, July 17, 2014 /PRNewswire/ -- Exelixis, Inc. (Nasdaq: EXEL) is a development stage biotech company. EXEL developed two cancer treatments cabozantinib (Cabo, Cometriq) and cobimetinib (Cobi). Both use small molecules as the active component. The company has a partnership with Roche to commercialize, market and distribute cobi. Cobi is expected to earn approval in the treatment of melanoma by late 2015, after positive phase-three trial results earlier this week. Cabo is...

2014-01-22 11:47:15

‘Dihydroartemisinin-piperaquine is more effective than artemether-lumefantrine, and has fewer side effects than artesunate-mefloquine’ concludes a systematic review published by the Cochrane Infectious Disease Group, hosted by LSTM. Dihydroartemisinin-piperaquine is one of five artemisinin-based combination therapies currently recommended by the World Health Organization (WHO), and this review finds that it is also one of the most studied. The team of authors from South Africa, Kenya,...

2013-12-04 10:38:28

An analysis of patients from across the malaria endemic world suggests that a key antimalarial treatment could be improved by better dosing in young children Antimalarial drug resistance has hampered malaria control programs for almost 60 years. A key factor in combatting this threat is to ensure that all antimalarial drugs are deployed in a way that ensures that the maximum number of patients are completely cured. A study published this week in PLOS Medicine explores this issue by...

2013-11-14 13:04:52

Lower doses of the antimalarial drug primaquine are as effective as higher doses in reducing malaria transmission, according to a study published today in Lancet Infectious Diseases by London School of Hygiene & Tropical Medicine researchers. Primaquine is one of the few antimalarial drugs that targets the transmission stages of the malaria parasite, the gametocytes, and is therefore considered to be an important tool for malaria elimination. However, standard doses of the drug...

Additive Found In Dog Food May Prevent A Disabling Chemotherapy Side Effect
2013-09-20 08:47:59

April Flowers for redOrbit.com - Your Universe Online A chemical commonly used as a dog food preservative might prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol. A team of Johns Hopkins researchers have been working with cells in test tubes and mice to investigate the Food and Drug Administration (FDA)-approved dog food preservative. The preservative, an antioxidant called ethoxyquin, has been...

2013-03-21 16:13:24

Drug may be major advance as malaria has developed resistance to existing treatments Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and preventing malaria – a disease that kills more than one million people each year. The scientists have described the drug, and its effectiveness against mice infected with malaria, in the March 20 issue of Science...

2013-03-06 10:31:54

Early diagnosis and treatment with antimalarial drugs (ACTs–artemisinin based combination treatments) has been linked to a reduction in malaria in the migrant population living on the Thai-Myanmar border, despite evidence of increasing resistance to ACTs in this location, according to a study by international researchers published in this week's PLOS Medicine. These findings are important as this study suggests that alternative treatments are urgently needed to replace the failing...

2013-03-05 10:58:27

Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which is published in the scientific periodical Molecular Psychiatry, identifies a gene variant associated with an increased production of KYNA. The discovery contributes to the further understanding of the link between inflammation and psychosis — and might pave the way for...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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