Latest Quinolone Stories

Second FDA approval in four months demonstrates Putney's deep scientific capabilities PORTLAND, Maine, April 29, 2013 /PRNewswire/ -- Putney, Inc., a rapidly growing pharmaceutical company focused on the development and sale of generic prescription medicines for pets, has launched Enrofloxacin Flavored Tablets, the first and only FDA approved veterinary generic of Baytril® Taste Tabs®. Putney's Enrofloxacin Flavored Tablets are indicated for the management of diseases associated...

redOrbit Staff & Wire Reports - Your Universe Online A commonly-prescribed antibiotic could trigger potentially fatal irregular heart rhythms in some patients, officials from the US Food and Drug Administration (FDA) warned on Tuesday. Azithromycin, which is commonly sold as Zithromax or Zmax and is sometimes referred to as a “Z-Pack,” could cause the condition in patients who have an elevated risk of developing cardiovascular problems, reports Deborah Kotz of the Boston Globe....

Researchers track the emergence and global spread of healthcare associated Clostridium difficile Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously thought. The spread and persistence of both epidemics were driven by the acquisition of resistance to a frontline antibiotic. Unlike many other healthcare-associated...

MENLO PARK, Calif., Sept. 7, 2012 /PRNewswire/ -- Kalidex Pharmaceuticals, a privately-held anti-infective company, today announced the presentation of data on its lead development candidate KPI-10, a broad spectrum, next-generation fluoroquinolone, at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, September 9 through 12. The data describe the in vitro and in vivo activity of KPI-10 against a wide range of important gram-negative...

A new study by researchers at Johns Hopkins Bloomberg School of Public Health and Arizona State University found evidence that a strong class of antibiotics, banned by the FDA, is still in use in commercial poultry production. The study, published in Environmental Science & Technology, looked for drugs and other chemicals in feather meal. Feather meal is commonly added to chicken, swine, cattle and fish feed. The banned antibiotics belong to a class of antibiotics called...

In an analysis of a cohort that included nearly one million patients who had visited an ophthalmologist, patients who were taking oral fluoroquinolones had a higher risk of developing a retinal detachment, a serious eye condition, compared with nonusers, although the absolute risk was small, according to a study in the April 4 issue of JAMA. "Fluoroquinolones are one of the most commonly prescribed classes of antibiotics. Their broad-spectrum antibacterial coverage and high-tissue...

Last month, the California Supreme Court agreed to review a class-action lawsuit over the drug Cipro. Cipro is a brand name for ciprofloxacin, of a class of antibiotic drugs known as fluoroquinolones. Manufactured originally by Bayer, it is used for many types of infections including pneumonia, skin infections, urinary tract infections, bronchitis and joint infections, among others. The lawsuit argues that it was illegal for Bayer to pay a competitor to stay out of the market as part of a...

SANTA FE, N.M., March 28, 2012 /PRNewswire/ -- The overuse of antibiotics is "slowly killing us," said Shane Ellison, author of Over-the-Counter Natural Cures. "My daughter was 3 years old when she had her first emergency room visit. Suffering from high fever and chest pain, every muscle in her fragile body tensed for air. Her lungs were being attacked by pneumonia. The antibiotic penicillin saved her life," said Ellison, who is known as "The People's Chemist." "Today, antibiotics...

(Ivanhoe Newswire) -- A recent study has discovered that short-term use of the antibiotic cefpodoxime for treatment of bladder infections (uncomplicated cystitis) in women did not meet criteria for achieving clinical cure compared to ciproflaxacin, a drug classified as fluoroquinolone antibiotics, that is under concern for overuse and resulting in an increase in resistance rates. While fluoroquinolone has minimal adverse drug reactions when used in a 3-day regimen and high efficacy rates,...

Short-term use of the antibiotic cefpodoxime for the treatment of women with uncomplicated cystitis (bladder infection) did not meet criteria for noninferiority for achieving clinical cure compared with ciprofloxacin, a drug in the fluoroquinolone class of antibiotics for which there have been concerns about overuse and a resulting increase in resistance rates, according to a study in the February 8 issue of JAMA. The criteria for noninferiority was if the efficacy of cefpodoxime had been...