Latest Rakesh Jain Stories

2013-11-23 23:01:53

A new report published in the Proceedings of the National Academy of Science (PNAS) Early Edition details a study funded in part by the National Foundation for Cancer Research, which indicates magnetic resonance (MR) imaging may be able to discern which patients will benefit more from anti-angiogenic drugs. Bethesda, MD (PRWEB) November 23, 2013 A new report published in the Proceedings of the National Academy of Science (PNAS) Early Edition details a study funded in part by the National...

2013-11-05 10:55:56

Study confirms that vascular normalization is the way these drugs improve patient survival Advanced imaging techniques may be able to distinguish which patients' tumors will respond to treatment with anti-angiogenic drugs and which will not. In patients newly diagnosed with the dangerous brain tumor glioblastoma, Massachusetts General Hospital (MGH) researchers report, those for whom treatment with the anti-angiogenic drug cediranib rapidly 'normalized' abnormal blood vessels around their...

2013-10-02 10:34:29

Treatment with losartan increases drug delivery in animal models by opening collapsed tumor blood vessels Use of existing, well-established hypertension drugs could improve the outcome of cancer chemotherapy by opening up collapsed blood vessels in solid tumors. In their report in the online journal Nature Communications, Massachusetts General Hospital (MGH) investigators describe how the angiotensin inhibitor losartan improved the delivery of chemotherapy drugs and oxygen throughout...

2013-08-19 13:06:21

Rapid identification of changes in tumor blood vessels could help avoid ineffective therapies A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective. In their report receiving online publication in Nature Medicine, investigators from the Martinos Center for Biomedical Imaging at...

2012-09-20 16:58:57

MGH study identifies components responsible for therapy-blocking solid stress, suggests therapeutic strategies It's a high-pressure environment within solid tumors. Abnormal blood and lymphatic vessels cause fluids to accumulate, and the uncontrolled proliferation of cancer cells within limited space leads to the buildup of what is called solid stress. Both types of pressure can interfere with the effectiveness of anticancer treatments, but while strategies have been developed that reduce...

2012-04-09 09:51:29

Combining two strategies designed to improve the results of cancer treatment — antiangiogenesis drugs and nanomedicines — may only be successful if the smallest nanomedicines are used. A new study from Massachusetts General Hospital (MGH) researchers, appearing in Nature Nanotechnology, finds that normalizing blood vessels within tumors, which improves the delivery of standard chemotherapy drugs, can block the delivery of larger nanotherapy molecules. "We found that vascular...

2009-03-30 14:38:20

U.S. medical researchers say the positive effects of anti-angiogenesis drugs in treating brain tumors appears to result from edema reduction. The Massachusetts General Hospital scientists said the reduction in size of the brain tumors, called glioblastomas, appears to result primarily from reduction of the swelling of brain tissue and not from any direct anti-tumor effect. Angiogenesis is the formation of new blood vessels. The study involved treatment with the experimental drug cediranib and...

2009-02-25 06:00:00

JERSEY CITY, N.J., Feb. 25 /PRNewswire/ -- Psychiatric Congress 2009 announces Rakesh Jain, MD, MPH, one of the nation's leading experts in the field of mental health, as program chair. Dr. Jain is director of psychiatric drug research at the R/D Clinical Research Center in Lake Jackson, Texas. His research involves special interest in the therapeutic areas of depression and fibromyalgia. (Photo: http://www.newscom.com/cgi-bin/prnh/20090224/SF75086) "We are pleased to welcome Dr. Jain as...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'