Latest Ramoplanin Stories
With the "last resort" antibiotic Vancomycin now plagued by the first signs of bacterial resistance, a scientific collaboration centered at Duke University has identified how a candidate successor antibiotic known as Ramoplanin A2 can kill pathogenic bacteria by interrupting how they form their cell membranes.During a 12-year quest, the research team had to learn how to crystallize Ramoplanin's molecular structure at the crucial time and place that it interacts with the bacterium's membrane....
The United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance to Oscient Pharmaceuticals (Nasdaq: OSCI) for a U.S. patent relating to methods of use of Ramoplanin for the treatment of Clostridium difficile-associated disease (CDAD), a serious form of colitis. Ramoplanin is a glycolipodepsipeptide antibiotic positioned for Phase III development for the potential treatment of CDAD, pending the conclusion of ongoing partnership discussions. A Notice of Allowance is...
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