Latest Randomized controlled trial Stories

Researchers offer new framework to improve the safety and effectiveness of surgical procedures and implantable devices An international team of investigators co-led by Weill Cornell Medical College is offering a new framework for evidence-based surgery and device research, similar to the kind of risk and benefit analysis used in evidence-based medicine. "Currently, there is no dynamic research framework to systematically detect devices and surgeries that don't offer any benefits to...

MARIETTA, Ga., June 10, 2013 /PRNewswire/ -- MiMedx Group, Inc. (NASDAQ: MDXG), an integrated developer, manufacturer and marketer of patent protected regenerative biomaterials and bioimplants processed from human amniotic membrane, announced today that a randomized controlled trial (RCT) for the Company's EpiFix(R) wound care allograft has been published in the International Wound Journal. Parker H. "Pete" Petit, Chairman and CEO, said, "The results of this clinical trial were...

CLEVELAND, May 15, 2013 /PRNewswire/ -- Researchers from University Hospitals Case Medical Center's (UHCMC) Seidman Cancer Center will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials. Results from a large-scale, randomized trial demonstrated that the use of tailored, web-based videos delivering educational information to patients before an oncologist visit can significantly improve knowledge and...

NEW YORK, March 28, 2013 /PRNewswire/ -- An EmblemHealth project found evidence that practice redesign and embedded care management in general adult primary care practices using the Patient-Centered Medical Home (PCMH) model results in modest, but promising, reduction in Emergency Department (ED) visits and improved quality of care. The findings, reported in an independent study by University of Connecticut (UConn) researchers, were published online by the Journal of General Internal...

In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch, compared with other resuscitation solutions, was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA. Moreover, after exclusion of 7 trials performed by an investigator whose research has been retracted because of scientific misconduct, the analysis of the remaining studies...

Commentary sheds light on approval process for implantable body parts Technological advancements in medicine have allowed patients suffering from musculoskeletal conditions such as hip and knee pain to regain mobility and live relatively pain-free. But some "high risk" surgical devices that have been approved by the U.S. Food and Drug Administration (FDA) are not required to go through clinical trials, where a product is tested to determine its safety and effectiveness. "This could be...

Patients who received an implantable heart defibrillator in everyday practice had survival benefits on par with those who received the same devices in carefully controlled clinical trials, according to a new study that highlights the value of defibrillators in typical medical settings. Led by the Duke Clinical Research Institute and published Jan. 2, 2013, in the Journal of the American Medical Association, the study used data from a large national Medicare registry to assess the survival...

Practice may elevate chance of death, second heart attack When heart attack patients present in the emergency department with some degree of anemia, or anemic patients have a heart attack, physicians have a tendency, but not much guidance, about whether to provide a blood transfusion. The idea is that a transfusion could help more oxygen get to the heart. Recent national guidelines suggested that there simply isn't good evidence to encourage or discourage the common practice, but a new...

Patients with muscle invasive bladder cancer may experience less loss of blood and shorter hospital stays as a result of robotic-assisted surgery, new randomized study in the Journal of Urology About 30 percent of the more than 70,000 bladder cancer cases expected in 2012 are muscle invasive. In such cases, radical cystectomy is the preferred treatment. In a pilot trial, a team of investigators assessed the efficacy of open radical cystectomy (ORC) vs. robotic-assisted laparoscopic radical...

WINNIPEG, Manitoba, Dec. 11, 2012 /PRNewswire/ -- Doug Broeska, Ph.D., CEO of Regenetek Research Inc., an international medical research company with offices in Canada and India has announced that they are launching new web-based, self-managing, clinical trial software that amongst other things will be able to extend patient Registry information into individual patient case studies and aggregate the data with comparisons to cohorts. The company has so far specifically focused their...