Latest RANKL Stories

2013-02-06 10:59:33

New research in animals triggered by a combination of serendipity and counterintuitive thinking could point the way to treating fractures caused by rapid bone loss in people, including patients with metastatic cancers.

2012-07-18 10:29:08

Stress can promote breast cancer cell colonization of bone.

2012-07-18 06:37:41

Investigators from the Vanderbilt Center for Bone Biology have discovered that stress can promote the colonization of breast cancer cells in bone.

2012-06-18 11:28:54

Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.

2011-02-16 17:09:28

When doctors discover high concentrations of regulatory T cells in the tumors of breast cancer patients, the prognosis is often grim, though why exactly has long been unclear.

2010-04-19 15:04:00

THOUSAND OAKS, Calif., April 19 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN) today announced results of a preclinical study demonstrating a positive response to administration of RANK-Fc against mammary tumor formation in mouse models. OPG-Fc and RANK-Fc bind to and block the action of RANKL.

2009-11-25 15:15:00

The mammalian system for controlling bone remodelling also regulates fever.

2009-09-22 08:00:29

Researchers have identified a mechanism that may keep a well known signaling molecule from eroding bone and inflaming joints.

2009-09-15 07:57:12

In blood cells, the protein Bcl-xL has a well-characterized role in preventing cell death by a process known as apoptosis.

2009-08-26 14:36:01

U.S. researchers say immune system-based approaches may help in treating osteoporosis. The study, published in Clinical Immunology, links bone loss to the immune system's reaction to cholesterol-related oxidation -- cell and tissue damage from exposure to free radicals.

Word of the Day
  • Withering but not falling off, as a blossom that persists on a twig after flowering.
The word 'marcescent' comes from a Latin word meaning 'to wither'.