Latest Reactive oxygen species Stories
EXPANDED ABSTRACT KEY WORDS: * superoxide dismutase * reactive oxygen species Manganese superoxide dismutase (MnSOD)3 is a nuclear-encoded antioxidant enzyme that localizes to the mitochondria (1). Increased expression of MnSOD suppresses cancer phenotypes in a large number of human and murine tumors (2). MnSOD can also regulate tumor formation in MnSOD-overexpressing and MnSOD-deficient mice by modulating apoptotic and proliferation pathways in situ (3,4). The presence of MnSOD in...
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