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Latest Reactive oxygen species Stories

2012-01-17 13:24:51

Scientists at the University of York have made a significant step forward in isolating the cause of Parkinson's disease in younger adults. Research by a team in the University´s Department of Biology found evidence that movement disorders, including tremor and slowness of movement (bradykinesia), associated with Parkinson´s disease (PD) may be due to a defect in energy production in the nervous system. The advance may help to identify young adults who may be susceptible to the...

2011-12-20 18:12:13

It's rubbed on the skin to reduce signs of aging and consumed by athletes to improve endurance but scientists now have the first evidence of one of vitamin E's normal body functions. The powerful antioxidant found in most foods helps repair tears in the plasma membranes that protect cells from outside forces and screen what enters and exits, Georgia Health Sciences University researchers report in the journal Nature Communications. Everyday activities such as eating and exercise can...

2011-12-14 12:06:01

When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down. Simply put, that same "browning" process-known as oxidative stress-happens in the brain as Alzheimer's disease sets in. The underlying cause is believed to be improper processing of a protein associated with the creation of free radicals that cause oxidative stress. Now, a study by researchers in the University of Georgia College of Pharmacy has shown...

2011-12-12 12:08:56

For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes from cell metabolism to programmed cell death. Now, scientists from the Florida campus of The Scripps Research Institute have identified the importance of a novel protein-regulating mechanism -- called sulfenylation -- that is similar to phosphorylation and may, in fact, open...

2011-12-02 01:13:30

A diametric shift in the levels of two proteins involved in folding, moving and cutting other proteins enables accumulation of the destructive brain plaque found in Alzheimer's disease, researchers report. VPS35 is a protein that folds others into specific positions to unleash their functions. When levels are reduced as they are in aging, it unleashes the normally dormant BACE1, a protein responsible for beta amyloid plaque production, Georgia Health Sciences University researchers report...

2011-11-11 01:20:16

Study of hereditary Parkinson's finds that mitochondria can't be cleared out when damaged Current thinking about Parkinson's disease is that it's a disorder of mitochondria, the energy-producing organelles inside cells, causing neurons in the brain's substantia nigra to die or become impaired. A study from Children's Hospital Boston now shows that genetic mutations causing a hereditary form of Parkinson's disease cause mitochondria to run amok inside the cell, leaving the cell without a...

2011-11-10 11:00:00

Study of hereditary Parkinson's finds that mitochondria can't be cleared out when damaged BOSTON, Nov. 10, 2011 /PRNewswire-USNewswire/ -- Current thinking about Parkinson's disease is that it's a disorder of mitochondria, the energy-producing organelles inside cells, causing neurons in the brain's substantia nigra to die or become impaired. A study from Children's Hospital Boston now shows that genetic mutations causing a hereditary form of Parkinson's disease cause mitochondria to...

2011-11-04 23:00:27

New findings suggest that activation of the PKM2 enzyme may sensitize cancer cells to oxidative stress It has long been known that cancer cells use nutrients differently than normal cells. In recent years, the rapidly reemerging field of cancer metabolism has shed new light on the ways that cancers use glucose to grow and thrive, demonstrating that manipulation of an enzyme called PKM2 is important to this metabolic process. Now a new study led by a scientific team at Beth Israel...

2011-08-24 17:20:43

Cardiologists who perform heart operations using x-ray guided catheters are exposed to ionizing radiation at levels two to three times higher per year than those experienced by radiologists. Now, new research has found the first evidence that these constant, high levels of exposure cause changes at cell level that might represent the body's way of protecting itself against the harmful effects of radiation. The research, published online today in the European Heart Journal, found that among...

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2011-05-31 06:10:00

In addition to its damaging effect on the environment and its illegal smuggling into developing countries, researchers have now linked e-waste to adverse effects on human health, such as inflammation and oxidative stress "“ precursors to cardiovascular disease, DNA damage and possibly cancer. In a study published today, Tuesday 31 May, in IOP Publishing's journal Environmental Research Letters, researchers took air samples from one of the largest e-waste dismantling areas in China and...