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Latest Reactive oxygen species Stories

2008-07-14 09:01:11

Synta Pharmaceuticals Corp., (NASDAQ: SNTA) a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that it is appointing Michael P. Bailey Senior Vice President and Chief Commercial Officer. Mr. Bailey will join Synta August 4th, 2008. "Synta represents a unique opportunity - a pipeline of multiple, internally-generated, blockbuster-potential, high quality programs; a powerful research and...

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2008-03-26 10:40:00

Researchers pinpoint how resveratrol induces pancreatic cancer cell deathRochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function. The study is published in the March edition of the journal, Advances in Experimental Medicine and Biology.The study also showed that when the pancreatic cancer cells were doubly...

2007-02-02 18:00:52

By Corbin, Joseph F III; Teel, Amy L; Allen-King, Richelle M; Watts, Richard J ABSTRACT: The enhanced treatment of sorbed contaminants has been documented in modified Fenton's reactions; contaminants are desorbed and degraded more rapidly than they desorb by fill-and-draw or gas- purge desorption. The reactive species responsible for this process was investigated using dodecane as a model sorbent. Hydroxyl radical, hydroperoxide anion, and superoxide radical anion were generated...

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2006-03-27 14:00:00

A new Pacific Northwest National Laboratory study offers the most detailed picture to date on how oxygen can be made in frigid reaches far from Earth ATLANTA-- Some may be surprised to learn that bleach-blondes and the enabler of life elsewhere in our solar system have something in common. And, no, it's not intelligence. It is, in fact, hydrogen peroxide. But how that hydrogen peroxide emerges from ice to become life-sustaining oxygen has been unclear. Now, a new study at the Department of...

2005-11-03 15:23:23

Bethesda, MD - Scientists recently discovered an anti-aging hormone called Klotho. Now, a new study shows that this protein acts by increasing the cell's ability to detoxify harmful reactive oxygen species. The research appears as the "Paper of the Week" in the November 11 issue of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. The klotho gene, named after the Greek goddess who spins life's thread, is associated with preventing aging...

2005-06-07 18:48:41

Three studies in the June issue of Cell Metabolism offer additional insight into how the cells of mammals sense oxygen. Oxygen plays a central role in fueling cells, and oxygen deficiency underlies many disease conditions, including heart attack, stroke, inflammation, and cancer. The findings should help to resolve a long-standing controversy over the identity of mammalian oxygen sensors, according to the researchers. The studies report genetic evidence that the cellular powerhouses known as...

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2005-06-07 18:15:00

Researchers have produced the strongest evidence yet that mitochondria "” the organelles that generate energy to power the cell "” also monitor oxygen concentration in the cell. If oxygen slips below a critical threshold, the mitochondrial "sensor" triggers protective responses to promote survival. Understanding how the cell senses and protects itself against hypoxia (low oxygen) has both important basic and clinical implications for biology and medicine, said one of the study's...

2004-11-29 09:00:19

Greetings and Opening Remarks Harold Seifried, Program Director, Division of Cancer Prevention, Nutritional Sciences Research Group, National Cancer Institute; Margaret Chesney, Deputy Director, National Center for Complementary and Alternative Medicine, NIH; Paul Coates, Director, Office of Dietary Supplements, NIH Harold Seifried, Program Director, Division of Cancer Prevention (DCP), Nutritional Sciences Research Group (NSRG), National Cancer Institute (NCI), welcomed participants to...

2004-11-27 03:00:11

EXPANDED ABSTRACT KEY WORDS: * antioxidants * apoptosis * cancer therapy There is a well-documented association between increased consumption of antioxidants and decreased incidence of cancer (1- 4). These epidemiological studies are supported by animal-model and cell-culture studies correlating oxidative DNA damage to the process of carcinogenesis (5,6). For these reasons, antioxidant supplements are often recommended as part of a cancer prevention diet (7,8). However, the generation of...

2004-11-27 03:00:10

EXPANDED ABSTRACT KEY WORDS: * superoxide dismutase * reactive oxygen species Manganese superoxide dismutase (MnSOD)3 is a nuclear-encoded antioxidant enzyme that localizes to the mitochondria (1). Increased expression of MnSOD suppresses cancer phenotypes in a large number of human and murine tumors (2). MnSOD can also regulate tumor formation in MnSOD-overexpressing and MnSOD-deficient mice by modulating apoptotic and proliferation pathways in situ (3,4). The presence of MnSOD in...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.