Quantcast

Latest Receptors Stories

2013-06-17 09:57:47

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor. Now, an interdisciplinary collaboration between researchers at the University of...

2012-09-20 16:56:31

In the body's ongoing effort to maintain a healthy weight, an arsenal of cellular proteins called androgen receptors is critical for blocking fat accumulation. Now researchers reporting in the September issue of the Cell Press Journal Chemistry & Biology have discovered that naturally occurring steroids called glucocorticoids can thwart the receptors' activity, ultimately encouraging fat buildup. "This has implications in this era of an obesity epidemic," says senior author Dr. Michael...

2012-07-31 10:50:00

Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors. The investigators found that the protein encoded by this gene, called EPHA3, normally inhibits tumor formation, and that loss or mutation of the gene — as often happens in lung cancer — diminishes this tumor-suppressive effect, potentially sparking the formation of lung cancer. The findings, published July 24 in the Journal of the...

2011-12-19 16:10:54

UC Riverside discovery creates new blueprint for engineering drought tolerant crops. When a plant encounters drought, it does its best to cope with this stress by activating a set of protein molecules called receptors. These receptors, once activated, turn on processes that help the plant survive the stress. A team of plant cell biologists has discovered how to rewire this cellular machinery to heighten the plants' stress response — a finding that can be used to engineer crops to...

2011-11-24 11:40:32

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even if their bodies were less responsive to insulin, the hormone that lowers blood sugar. A new study from The University of Texas Health Science Center San Antonio challenges this. Knocking out one copy of the gene failed to increase the life span of male mice, and it only...

2011-08-11 22:06:11

Cancer needs blood. In fact, some cancer medications work solely to slow or prevent cancer cells from creating new capillaries, choking off their much-needed blood and nutrient supply to halt the growth of tumors. In a paper published online Aug. 8 in the Proceedings of the National Academy of Sciences, researchers at Stanford University describe the creation of a new type of engineered protein that is significantly more effective at preventing the formation of blood vessels by targeting not...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
Related